| Gene ID | Annotation | Chromosome | Start | End | Strand |
|---|---|---|---|---|---|
| XP_032891153.1 | BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1 | NC_045971.1 | 17592520 | 17667893 | - |
| CDS | |||||
| XP_032891153.1 | |||||
| Transcript |
| - |
| Protein |
| XP_032891153.1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | E3|E3 activity RING|RING |
| Ubiquitin Family | E3|E3 activity RING|U-box |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00097 | zf-C3HC4 | Zinc finger, C3HC4 type (RING finger) | Domain | Interproscan |
| PF00533 | BRCT | BRCA1 C Terminus (BRCT) domain | Family | Interproscan |
| PF12820 | BRCT_assoc | Serine-rich domain associated with BRCT | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001357 | Domain | BRCT domain | Interproscan |
| IPR001841 | Domain | Zinc finger, RING-type | Interproscan |
| IPR011364 | Family | Breast cancer type 1 susceptibility protein (BRCA1) | Interproscan |
| IPR013083 | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR017907 | Conserved_site | Zinc finger, RING-type, conserved site | Interproscan |
| IPR018957 | Domain | Zinc finger, C3HC4 RING-type | Interproscan |
| IPR025994 | Domain | BRCA1, serine-rich domain | Interproscan |
| IPR031099 | Family | BRCA1-associated | Interproscan |
| IPR036420 | Homologous_superfamily | BRCT domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13763 | BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0000724 | Biological Process | double-strand break repair via homologous recombination | Interproscan |
| GO:0003677 | Molecular Function | DNA binding | Interproscan |
| GO:0004842 | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0006281 | Biological Process | DNA repair | Interproscan |
| GO:0006974 | Biological Process | DNA damage response | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0009048 | Biological Process | dosage compensation by inactivation of X chromosome | Interproscan |
| GO:0031436 | Cellular Component | BRCA1-BARD1 complex | Interproscan |
| GO:0035066 | Biological Process | obsolete positive regulation of histone acetylation | Interproscan |
| GO:0035067 | Biological Process | obsolete negative regulation of histone acetylation | Interproscan |
| GO:0043009 | Biological Process | chordate embryonic development | Interproscan |
| GO:0045717 | Biological Process | negative regulation of fatty acid biosynthetic process | Interproscan |
| GO:0045944 | Biological Process | positive regulation of transcription by RNA polymerase II | Interproscan |
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| GO:0070531 | Cellular Component | BRCA1-A complex | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| - | - | - | - | - | - |