| InterPro term | Type | Description | Source |
|---|
| IPR001631 | Family | DNA topoisomerase I | Interproscan |
| IPR008336 | Domain | DNA topoisomerase I, DNA binding, eukaryotic-type | Interproscan |
| IPR011010 | Homologous_superfamily | DNA breaking-rejoining enzyme, catalytic core | Interproscan |
| IPR013030 | Homologous_superfamily | DNA topoisomerase I, DNA binding, N-terminal domain 2 | Interproscan |
| IPR013034 | Homologous_superfamily | DNA topoisomerase I, DNA binding, N-terminal domain 1 | Interproscan |
| IPR013499 | Domain | DNA topoisomerase I, eukaryotic-type | Interproscan |
| IPR013500 | Domain | DNA topoisomerase I, catalytic core, eukaryotic-type | Interproscan |
| IPR014711 | Homologous_superfamily | DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type | Interproscan |
| IPR014727 | Homologous_superfamily | DNA topoisomerase I, catalytic core, alpha/beta subdomain | Interproscan |
| IPR018521 | Active_site | DNA topoisomerase I, active site | Interproscan |
| IPR025834 | Domain | Topoisomerase I C-terminal domain | Interproscan |
| IPR036202 | Homologous_superfamily | DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily | Interproscan |
| IPR048045 | Domain | DNA topoisomerase I, DNA-binding domain | Interproscan |
| IPR051062 | Family | DNA topoisomerase IB | Interproscan |