Detailed information of Bpl_scaf_64005-10.9 in Gigantidas platifrons Gene info
Gene IDAnnotationScaffoldStartEndStrand
Bpl_scaf_64005-10.9TYROSINE-PROTEIN KINASE RECEPTORBpl_scaf_640059388071002565-

Gene Structure
More details in Jbrowse Sequence
CDS
Transcript
Protein

Gene family
Gene familySubfamily
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Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00757Furin-likeFurin-like cysteine rich regionDomainInterproscan
PF01030Recep_L_domainReceptor L domainRepeatInterproscan
PF07714PK_Tyr_Ser-ThrProtein tyrosine and serine/threonine kinaseDomainInterproscan

InterPro
InterPro termTypeDescriptionSource
IPR000494DomainReceptor L-domainInterproscan
IPR000719DomainProtein kinase domainInterproscan
IPR001245DomainSerine-threonine/tyrosine-protein kinase, catalytic domainInterproscan
IPR006211DomainFurin-like cysteine-rich domainInterproscan
IPR006212RepeatFurin-like repeatInterproscan
IPR008266Active_siteTyrosine-protein kinase, active siteInterproscan
IPR009030Homologous_superfamilyGrowth factor receptor cysteine-rich domain superfamilyInterproscan
IPR011009Homologous_superfamilyProtein kinase-like domain superfamilyInterproscan
IPR016245FamilyTyrosine protein kinase, EGF/ERB/XmrK receptorInterproscan
IPR017441Binding_siteProtein kinase, ATP binding siteInterproscan
IPR020635DomainTyrosine-protein kinase, catalytic domainInterproscan
IPR036941Homologous_superfamilyReceptor L-domain superfamilyInterproscan
IPR050122FamilyReceptor Tyrosine KinaseInterproscan

PANTHER
PANTHER termDescriptionSource
PTHR24416TYROSINE-PROTEIN KINASE RECEPTORInterproscan

Gene Ontology
GO termsCategoryDescriptionSource
GO:0004672Molecular Functionprotein kinase activityInterproscan
GO:0004713Molecular Functionprotein tyrosine kinase activityInterproscan
GO:0004714Molecular Functiontransmembrane receptor protein tyrosine kinase activityInterproscan
GO:0005524Molecular FunctionATP bindingInterproscan
GO:0005887Cellular Componentplasma membraneInterproscan
GO:0006468Biological Processprotein phosphorylationInterproscan
GO:0007169Biological Processcell surface receptor protein tyrosine kinase signaling pathwayInterproscan
GO:0007275Biological Processmulticellular organism developmentInterproscan
GO:0008284Biological Processpositive regulation of cell population proliferationInterproscan
GO:0009925Cellular Componentbasal plasma membraneInterproscan
GO:0016020Cellular ComponentmembraneInterproscan
GO:0022008Biological ProcessneurogenesisInterproscan
GO:0033674Biological Processpositive regulation of kinase activityInterproscan
GO:0043066Biological Processnegative regulation of apoptotic processInterproscan
GO:0043235Cellular Componentreceptor complexInterproscan

KEGG pathway
KOEnzymeEnzyme IDpathwaymapIDSource
K04361EGFR, ERBB1; epidermal growth factor receptorEC:2.7.10.1
Ras signaling pathway ko04014PMID: 28812709
Rap1 signaling pathway ko04015PMID: 28812709
MAPK signaling pathway ko04010PMID: 28812709
MAPK signaling pathway - fly ko04013PMID: 28812709
ErbB signaling pathway ko04012PMID: 28812709
HIF-1 signaling pathway ko04066PMID: 28812709
FoxO signaling pathway ko04068PMID: 28812709
Calcium signaling pathway ko04020PMID: 28812709
Phospholipase D signaling pathway ko04072PMID: 28812709
PI3K-Akt signaling pathway ko04151PMID: 28812709
Cytokine-cytokine receptor interaction ko04060PMID: 28812709
Endocytosis ko04144PMID: 28812709
Apoptosis - fly ko04214PMID: 28812709
Focal adhesion ko04510PMID: 28812709
Adherens junction ko04520PMID: 28812709
Gap junction ko04540PMID: 28812709
Regulation of actin cytoskeleton ko04810PMID: 28812709
GnRH signaling pathway ko04912PMID: 28812709
Estrogen signaling pathway ko04915PMID: 28812709
Oxytocin signaling pathway ko04921PMID: 28812709
Dorso-ventral axis formation ko04320PMID: 28812709
Pathways in cancer ko05200PMID: 28812709
Central carbon metabolism in cancer ko05230PMID: 28812709
Choline metabolism in cancer ko05231PMID: 28812709
MicroRNAs in cancer ko05206PMID: 28812709
Proteoglycans in cancer ko05205PMID: 28812709
Pancreatic cancer ko05212PMID: 28812709
Glioma ko05214PMID: 28812709
Melanoma ko05218PMID: 28812709
Bladder cancer ko05219PMID: 28812709
Prostate cancer ko05215PMID: 28812709
Endometrial cancer ko05213PMID: 28812709
Breast cancer ko05224PMID: 28812709
Non-small cell lung cancer ko05223PMID: 28812709
Epithelial cell signaling in Helicobacter pylori infection ko05120PMID: 28812709
Hepatitis C ko05160PMID: 28812709
Human papillomavirus infection ko05165PMID: 28812709
EGFR tyrosine kinase inhibitor resistance ko01521PMID: 28812709
Endocrine resistance ko01522PMID: 28812709

Expression pattern
 1. Expression trend for Bpl_scaf_64005-10.9 global RNA-seq network
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