Gene detail

Detailed information of Bpl_scaf_62441-5.7 in Gigantidas platifrons Gene info

Gene ID	Annotation	Scaffold	Start	End	Strand
Bpl_scaf_62441-5.7	CBL	Bpl_scaf_62441	483291	522145	-

Gene Structure

More details in Jbrowse Sequence

CDS

Transcript

Bpl_scaf_62441-5.7

ATGGCAAGAAAACAGGGAATTGTCCAGAACCAGAATGACAGTGATGAGGAAGATGATATTGAATTTGGATTTAAACAGACAGAGACAGAAAACTGTAAATCGAATCCTAAATTCCTACTGAAGAAATCATATGATGGTGTCTGGACAATTGTTTCGTGGAAGATTTTCCGACAGACGCTTCATGAGTCACACCCAATAAGTTCTCCACTGGAAGCTATGGCACTAAAGTCCACTATAGACTTGACTTGTAACGACTTTATTTCAATATTTGAATTTGATGTGTTTTCTAGATTATTCCAGCCCTGGATCAATCTACTACGGAATTGGAATGTATTAGCAGTGACACATCCTGGCTATGTGGCTTTTCTTACATATGATGAAGTTAAAGCTCGGTTACAAAAATATGTCAACAAACCAGGAAGTTATGTGTTCAGATTGAGCTGTACCAGGTTAGGACAATGGGCAATAGGCTATGTAACAGCAGAGGGACAAATTTTACAGACAATTCCACAGAATAAGTCCTTGTGTCAGGCACTTCTAGATGGTCAAAGAGAGGGATTTTTTAAATACCCTGATGGAAGAAGCATTAACCCAGATTTAAGTTATTTGGTCCAAGATAGTCAAGAAGACCATATAAAAGTTACACAAGAACAGTATGAACTCTATTGTGAGATGGGATCAACGTTTCAGTTGTGTAAAATCTGTGCAGAAAATGATAAAGACATTAAAATAGAACCATGTGGTCATTTATTATGTACACCTTGTTTAACACAGTGGCAGGATTCTGATGGACAGGGCTGTCCATTCTGTAGATGTGAAATCAAAGGTACAGAGCAGGTGATCGTCGATCCATTTAATCCACACCCACAGAAACGTACACAACACATGCATGTTGCACACGACGAGGATGATGATATTGATGTTAGAGAGCGGTCTTCACCCTTTGACTCCCCTGGGGTGGGGAAGCGAGATTTACCCCCACCCCCACCACCAGTGCCACCAAGAAGATCTTCACCCTTGCCATCACCTACAGTTTCACCAACATCATCACCTAGACCACCATGCCGAAGACAGCTGCCTCCAACACCTCCATCAGAGGATAAAAATATGATACTTCAACCTGTTAAAAAAACAGTATGTACAGATACTGATGGTTCAGGTATATCATATGCCGAATTACGCTACGACGTACCAGCATCCTCGTCATCTACTTCACATCATCCAAATACAGCAAATAATTGTTTATATCTGTCTCAGCCTGACACGGACACTGTAATGACAGATGAAACCGTTCAAGATGAGTATTCAATGCCAAAGGGAGGTAAAACTCCTCTCCATAGAGTTCCAACAGACTATGACCTTCCACCTTTACCTGCTCCCAGAAAAAATATACCAGGAGATCCATACAAAAAAGTAGACAGTAATTCAGATATACCATTACCTGTACGGAATCGTGATAGTCGAGAAAAATTAAAGGAAAATTGTGACAGTAATAAAGAAAATAGTGTGGATGAACAATCTGTGGACCATTTAGTTCAAAAAGGATATGACAGATTACGAGTTGTCGATGCTCTTCGTGTGGCCAGAAATAACTTACGAATGGCAGAAGACATTTTGGAGACTTTTGTTGGAAATTAACTCTTCTTTTTCTACTCTTTTTATAAATGTGATTTTTGTCAATCAGACACTTTTTTCTACTATTTTTCCATTATCTTTTTTTTTTCTATCAAATAATCTCCCTTTAACAAAGTTGTAATCCGTTTATTTAATTTTCATTACGACTTCTTACTCCTCAAGTAAAATTTTGTTTTAAACGCAACATATTTACTGCTTAGATTTGGCCCTATGGTAAGTTCAGGGATGAATATTTTTCTGTTATTTAAATGATTTCAGCTATTTTCCTCTAAATATAAATTCCGAAAGTTGCAGTACATTATCTGAACAGGTCACAAATGCAGGGTTTGAAAGGTGGTGTAGATGGCTTCAGCTATTTTCATTTATTTTCAGTTATTTTATTTTCTAACCAGGATCCCTGTAAATTTAAGCAGCACTTTTTGTCATTAAATTTATGTACTGACATGAACCATGTCCTCAACATAGTCAATTAATGGACTTTTTCTGGTCTTTGAGCCCCAAGGCTAAAAGGTCAGTTAAAAATTTGTTAGTGTTCCTATTATTTTAATGCTACCATACATGTATTAAAATAGATATCAGATTGAAAATAAGGTAATCTACCTTACTGATTTAGGAGCATCCTGCCAGATGTGAAAAAAGCTGTCAAAGGGGTCAAATTACCAAATTTATTCAATATAAGGTAGTACTATATAATGAGGACTTCAGTCTCAAATGATGAGAAATCAGGGTCCAAAAAGTGGGGAAAGGGGCCAATCTCATGTTTTCTTTAAAATGTATTAGATTAAATAAAACAAGTTTAATGACAAATTTATTCATGTATTTTACAGTCATCTTGTTTGTTCTCTTCATGTTTACATTCTGTGGTTGTATCGCGGTACTTAGATGGATCTTTTAACCGGTCCAAAGCAATAAAGTCATATGACTAATCTAATATAATGGTGCCAATTGAAGTAGATATGCTTAGCACTGTCTAGTCAAAACATTATAAGACATTTTAAAATTCAGATTTAATTTGTTAAAGGGAGGTAATTTTATGTTTATTCAGGTGGAATTTCTGCTGGCAGGACTTTATATACATACATATGTATATATACTGTTTTTGTCAGCTTTAATTTTGTTGCTTAATTCAAGTTTAACCACTTACACATTTGACTTTTGAAAACTTGTAAATTGCAATATTTAGATAAGTTACTTGTATAAAAACAAATATTTATACTTATGTACAGAGGTATGAAATTTTGTGAATTTATGTAGATTTGTTTAATATTATCAGTAGGCTATTTATCAAATTACATTTTTTCGTTTTTAATATTTGTTGCCTATACAAATACTACTACAATTTTGTTTTTCTGCTTGAAAGCACCATATTAGATTGTTCAGTATTTTTATGAAGTCATCATACCAGCAGATTGTTTACAATTTACTGTAGATTCTAAACATCCTGTGAGCATAATATGACAATATATTTAAAGTTTTGATATATTTTTTTCTAAAGTTTATAATATACTTTGCAAGAATATGACACATTTTTCAAATAAAGTGGAAAGTGAATGACCATTAATAGCATACCCAGGCTGATATTGTATTATCAGTCCAACTGATGTCAAAACACCATATCAGCATGGTCTGATATGCAATATTAGCCTGGTCCATATTTTTCAGATCAATTGCATATTAGTATATAATAAAAATATTAAAACATGAAACATTACCTTTTCCATATCAGCCTCGTTATCATCTCCAAACCAATATCGGCCCACCTTGGATCGATATGGGGGTCTCTGGATGATAACCAGACCGATATGAGAGAGGTCTTGCTTTAATCTGTTTTTATTACATACTTAGTTAAAATAAAGGCATTTTTGTATGACCAATATGACCGGAAGTAAACTTTCAATATTTTCGCACCCCGGGAAAATAACTGGTTATTGGATTACTACAAGATCATTTCCATATCGGCCCGGGCCAATATGGGTGTCTCTTTTCTAGATGTCGGAAGTATGTAATAAATAGTTTTATATGGGTGTCTCTGGATGATAACCAGGCCAATATGGAAATGCCCATGTATTATTAATCTGTATTTATTTACTGGTAGGTCACAGATATTTTGTTGTTTCTTTTATAAAATTAAATATATTTGGCCTTGAATGACATTGACAGAGAGAGAACATGTTGAAATGATATGGCAGATATTTTTTTTTGCAAATCAATAAAAACTGTGCTTGTGTTTGTATTGCTGTTAAGTCATGTTTATTCTTGGGGTATAACTTTTCATGGATTTCATCATTTATTTTTCAAACCAAGGATTAAAAACAAAATATAAATGTCCCCTCATGGCTATTGTGAAGCCCTTACTAATTAGATTATATAACTTGTCTGGCAGTATTATGCTGTTACTATTGTTACATGTAAAACATGAAATAAAGTGCAAAACAAAATTACTTGGTGTACATATATTTAAGGGGAGACAACTTCACTTGGAACTATCAAGAGGGAAATTAAGCATACGACTGATGCAGATTGATTATCATACAGGGGAGATAACTAATGAATGTTTAACTAACTTTATTTTTGTTATCTATTTTCACCAGTTAAAAGATACAGTTGAATTCTGTTATAACTTAAATGTGTGCAATTATATTTAAAAAAATCTGCACATTCATTGCCTATTTTAAGAACAGTATTTGGAAGGAATAAGTCAATACTTTATTCTTCTGTAAAGATTCCTTTTAATAACATATCTTCATTGTCACACATCACTGATTACAGTAATTCTGATTGATATGTAATATAGAATGATTGATTTTCAAGCTTGTTAAAAACAAATCAAACAGGATCAGTATTTAATACAACATTGTTTGTCATTACATATTTAAGAATCAGACAATTAAAGTACCGGTAATTATGTACCATTTGTTGAAGATCTCAATACATTTCATAGAAACAATGGACTCAAAACATTTCAAAGGTTTTATTTTTAGCGAAAAACAATATTTTACGAACTGAAGCAGAAGAATTTGTCAATAATCTAACAATGCAAATGCAAAAATTCTTTTAAAGAACACTTTCCCTTTTTCTATTTAGAATTTTTATATCCAGTCTCAGAAAATTCTCTGGATTTATAAAGTTTATATCACTCAATTACAAAATATTTCTCAACTGGTAATAAAAACCTTATAAAGATTTTGTTTCTTATATTTTCCATAAGCTACACACATGTAATAAAACATGGAATATGTCCTGACTCCTAACACAAATATGTTATGACCCCTAATACAAATATGTTATGACCCCTAACACAAATATGTCCTGATCCCTAATACAAATATATCCTGACCCCTAACACAAATATGTCCTGACTCCTAACACAAATATGTTATGACCCCTAATACAAATATGTTATGACCCCTAACACAAATATGTCCTGACCCCTAACACAAATTTGTCCTGACCCGTAACACAAATATGTCCTGACCCCTTATACAAATATGTCCTGACCCCTAACACAAATATGTCCTGACCCCTAACACAAATATGTCCTGACCCCTAATACAAATATGTCCTGACCCCTAACACAAATATGTTCTGACCCCTAACACAAATATGTTCTGACCCCTAATACAAATACAGTTAAGCCTGCCACTGCAGTCACCGTCGTGGAAAATTTCATATGAATTGAACCCTAATACAAAAAATACCAACCTCCAATGCAAAAAAGTACCAACCTCCAATACAAAAAGTACCAACCTCTATTCCAAAAAGTACCAACCTACAATTCAAAAAATACCAACCTCCAATACAAAAAAGTACCAACCTCCAATACAAAAAGTACCAACCTCCAATACAAAAAAGTACCAACCTCCAATACAAAAAGTACCAACCTCCAATACAAAAAGTACCGACCCATAATACAAAAAATACCAACCTTCAATACAAAAAAATACAGAATCCTAATTCAAAAAGTACCAACTTCCAATTAAAAAAAATACCAACCTCTAATACAAATAAGTACTGACTCTTTAAACAACAACTTCTGATCACTGTTTTGCTTGACAAATTAGATACTGTACTTAATTATAACATAGGACTTACCTGAACATTGTGGAAAGAAATTTCAATAAAAATTTATAGACTTGAATTATAAGAATTTTTACTCAAATTTGCAATGGTAATGTCATATTTTGTATGTTCAGTGAAAATGTGTCTCATTAAAAGAATGGAAGCAGAGTATTGAATACTATAAATCTATTTTTAACTTGCTCATAGATCCATTCCATTATAA

Protein

Gene family

Gene family	Subfamily
Ubiquitin Family	E3\|E3 activity RING\|RING

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02761	Cbl_N2	CBL proto-oncogene N-terminus, EF hand-like domain	Domain	Interproscan
PF02762	Cbl_N3	CBL proto-oncogene N-terminus, SH2-like domain	Domain	Interproscan
PF13920	zf-C3HC4_3	Zinc finger, C3HC4 type (RING finger)	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001841	Domain	Zinc finger, RING-type	Interproscan
IPR009060	Homologous_superfamily	UBA-like superfamily	Interproscan
IPR011992	Homologous_superfamily	EF-hand domain pair	Interproscan
IPR013083	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	Interproscan
IPR014741	Domain	Adaptor protein Cbl, EF hand-like	Interproscan
IPR014742	Domain	Adaptor protein Cbl, SH2-like domain	Interproscan
IPR015940	Domain	Ubiquitin-associated domain	Interproscan
IPR017907	Conserved_site	Zinc finger, RING-type, conserved site	Interproscan
IPR024159	Domain	Adaptor protein Cbl, PTB domain	Interproscan
IPR024162	Family	Adaptor protein Cbl	Interproscan
IPR036860	Homologous_superfamily	SH2 domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23007	CBL	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0001784	Molecular Function	phosphotyrosine residue binding	Interproscan
GO:0004842	Molecular Function	ubiquitin-protein transferase activity	Interproscan
GO:0005509	Molecular Function	calcium ion binding	Interproscan
GO:0005515	Molecular Function	protein binding	Interproscan
GO:0005886	Cellular Component	plasma membrane	Interproscan
GO:0007165	Biological Process	signal transduction	Interproscan
GO:0007175	Biological Process	negative regulation of epidermal growth factor-activated receptor activity	Interproscan
GO:0017124	Molecular Function	SH3 domain binding	Interproscan
GO:0023051	Biological Process	regulation of signaling	Interproscan
GO:0030971	Molecular Function	receptor tyrosine kinase binding	Interproscan
GO:0045121	Cellular Component	membrane raft	Interproscan
GO:0061630	Molecular Function	ubiquitin protein ligase activity	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K04707	CBL; E3 ubiquitin-protein ligase CBL	EC:2.3.2.27	Ubiquitin mediated proteolysis	ko04120	PMID: 28812709
			ErbB signaling pathway	ko04012	PMID: 28812709
			Endocytosis	ko04144	PMID: 28812709
			T cell receptor signaling pathway	ko04660	PMID: 28812709
			Insulin signaling pathway	ko04910	PMID: 28812709
			Pathways in cancer	ko05200	PMID: 28812709
			Proteoglycans in cancer	ko05205	PMID: 28812709
			Chronic myeloid leukemia	ko05220	PMID: 28812709
			Bacterial invasion of epithelial cells	ko05100	PMID: 28812709

Expression pattern

1. Expression trend for Bpl_scaf_62441-5.7 global RNA-seq network