| Gene ID | Annotation | Scaffold | Start | End | Strand |
|---|---|---|---|---|---|
| Bpl_scaf_23154-2.11 | NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED | Bpl_scaf_23154 | 215364 | 238449 | + |
| CDS | |||||
| Bpl_scaf_23154-2.11 | |||||
| Transcript |
| Bpl_scaf_23154-2.11 |
| Protein |
| Bpl_scaf_23154-2.11 |
| Gene family | Subfamily |
|---|---|
| - | - |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02146 | SIR2 | Sir2 family | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR003000 | Family | Sirtuin family | Interproscan |
| IPR026590 | Domain | Sirtuin family, catalytic core domain | Interproscan |
| IPR026591 | Homologous_superfamily | Sirtuin, catalytic core small domain superfamily | Interproscan |
| IPR029035 | Homologous_superfamily | DHS-like NAD/FAD-binding domain superfamily | Interproscan |
| IPR050134 | Family | NAD-dependent sirtuin protein deacylases | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11085 | NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0002039 | Molecular Function | p53 binding | Interproscan |
| GO:0003714 | Molecular Function | transcription corepressor activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005637 | Cellular Component | nuclear inner membrane | Interproscan |
| GO:0005654 | Cellular Component | nucleoplasm | Interproscan |
| GO:0017136 | Molecular Function | histone deacetylase activity, NAD-dependent | Interproscan |
| GO:0033553 | Cellular Component | rDNA heterochromatin | Interproscan |
| GO:0045892 | Biological Process | negative regulation of DNA-templated transcription | Interproscan |
| GO:0070403 | Molecular Function | NAD+ binding | Interproscan |
| GO:0070932 | Biological Process | obsolete histone H3 deacetylation | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K11411 | SIRT1, SIR2L1; NAD-dependent deacetylase sirtuin 1 | EC:3.5.1.- | FoxO signaling pathway | ko04068 | PMID: 28812709 |
| AMPK signaling pathway | ko04152 | PMID: 28812709 | |||
| Cellular senescence | ko04218 | PMID: 28812709 | |||
| Glucagon signaling pathway | ko04922 | PMID: 28812709 | |||
| Longevity regulating pathway - mammal | ko04211 | PMID: 28812709 | |||
| Longevity regulating pathway - worm | ko04212 | PMID: 28812709 | |||
| Longevity regulating pathway - multiple species | ko04213 | PMID: 28812709 | |||
| MicroRNAs in cancer | ko05206 | PMID: 28812709 | |||
| Amphetamine addiction | ko05031 | PMID: 28812709 |
| 1. Expression trend for Bpl_scaf_23154-2.11 global RNA-seq network |
Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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