Gene detail

Detailed information of Bpl_scaf_2275-4.3 in Gigantidas platifrons Gene info

Gene ID	Annotation	Scaffold	Start	End	Strand
Bpl_scaf_2275-4.3	TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG	Bpl_scaf_2275	331265	369541	-

Gene Structure

More details in Jbrowse Sequence

CDS

Bpl_scaf_2275-4.3

ATAGAGGGAGGTATTGCCCAGGCTGTCCCAGAACACCCTAAAAGAGATAACATTTTCTCCCTCAGCACGGCTTTTGGTGATGCTTACTTGTTTCAGGCATTATCATCTACAGAGGTAGAGAATTGGATTTGTGCCATACATTCAGCATGTGCTTCATCGTTTGCACGACAACATGGAAAAGATAATACATTAAAACTCATCAAAAGTGAACAGCACAAGTTGGAAAATAACATTGATGTGGATGTTAAGATGAAGAAGATGGCTGAGTTACAACTAACAGTGGTAACAGACCCAAGAAGTCGTCAAGCCATCATCAAACAGATTGCCCAATGGGAAGAGAATTTAGAAAAGCTATATATAGAACAATACAGACAACGATGTTACATATCTACGTTACAAGGAACAGAACTACCCAATCCTAAGGTTTTGTTAGCTAATGCATCCAAGACTACAAAAGCAACATTAGGAAAGCTTGGTGTATTTACTGTGACATCATTCCATGCGTTGGTAGCTGCAAGACGCCCTCTAGTGGTACCAAACATATATGGCAAGGGAAGTCATAAAGGAGGAATGCTGTCTCCGAGAGGTGATGGGACGTTCAAGTATAACTCTAAAGTTACTGCTCCAGTAACTAACTTGGACACATCGTCAGTGTATAAAGCTACTGATATAGATGAAGTTGTCGCTGAACTCTATAGAGATGTTCCTGATGGCCTGTCTGATAATTCTATGTCAGAAGAAAACTCTTTAGCTGAATCTCTGTCACGAATCTCTCTACCAAATCAACAGACAATTTTGGTCAATGTTAACAAGCACACCATTATACAAGATCTCTTAGAGTCTGTGTGTGGTAAACGACAGTTAAATTTAGAAGACCATTATGTACGTGTGAAGTTACCCAATACACCAGCAGGGGTTTATACTATACCAGAACCTCAAGAAATTATCAGAAAAATGAAATATGAATCTATAGAAGTGTGTGAAAAAAATGTCTTCCAAGTTGATCTGGTAAAATCTCAGAATGAGACAGAATTTGGGTTCGCTGTAGAAGCTGAGTTAGCTCAGAGTTTTGAGCGAGACGACGAGTTAAGACTGTACGTCAGCAATGTTTTACCTGCCAGTGTGGCCATTCAAGCAGGTTTAATGATCGGAGATGAAATTCTTGTGATAAATGGGAAAGTTGTATCAGAACTAGATATGGTGTATATTGAAAACTTGTTGCACACGTCACAGTCCCTGTGTTGTACCATAAGGTCTATACATACCCAGAGATCAACATCCTCACAGAAGTCGGGGGAAATTGATAACATGATGTGTCCCCCTCCACCCAGCCAGTCACGCATCAGTGAAGATACCCTTGGCCATCTTATAGTCCCATCACCAGCAGACAGTGGAAGTTTATCAAATAAAAGTTTACAGTCCAATTCACAATCAGATGTGTCTACAAACCAAATAGATGCTCTCTTGTCGGGTGCAGATCAAGTGACAGCTATATGTCGTAGAGATATAGACCCCAAACTAGCTGAGAGTTTAAAGGGGACTAAGTCATTGTCAGAAGCCCAAAAGTTACGGAAAGTCATCATGGAACTGATTGATACAGAGAGAGCTTATGTAAAGGATTTAGAATTTCTAATTGAGCGGTACCTGGAACCACTGAAGGAGGAGACATTTCTATCCAGTGAAGACGCTTACCATCTGTTTGGAAATATACATGAAATTTCTCAGTTCCAGAAGCAATTCCTTCAAAGTCTAGAGGAAGCCATGCAACTAGAAGGAGATTTTCTTGCCATTGAAGACCCAAAATTATTCAGGAGAGTGTTATTTTCACTTGGTGGATCTTTCCTGTTTTATGCCAACCACTTTAAAGTATACAGTTCATTTTGTGCTAGTCATACAAGATCTCAGAAAATTCTTAACCCAGAAACAAATGTTGCCCTGAAAGAATTCCTACAGGCCCGGAACCCTAAACAACAACACTCTGCTACACTGGAGTCATATCTGATCAAGCCTATACAACGAATACTTAAATATCCCCTCTTACTTCAAATGTTGTGTAACTTGACAGATCAAGATACAGATGAACATTATCACCTGTCAGAGGCTCTAAAGGGTATGGAAGCTGTGGCAGAACACATTAATGAAATGCAGAAAATATTCGAAGAATATGGTTCTGTGTTTGATGAATTATCTAAAATGTTTAGAGAAATCCATCCTCATAAAAAGCCGGTTGATCTAAGTGTAGGGGAGCTACAGATGTATGGTACGGTGGAATGGTGCAATATTTGTGATAGTCTGGGTAAAGTCAAGAAAAATCTAGATCTTGAAAACATTGTTTTCGTCTTCAGAACTGGAGTTGTCTTTCTTTGTAGAGAGAAAGTTAAGAAAAGAAAATCAAAGAGTAATACTAAGGGAGGTAACACAGATCCAATATTTGAGTTCCATGAAAGATTTAGGACACTAATTCCAGTACAGGAAGTCCAAGTGCAAGGAGGTCGTGTCAGTGATATGGACAGACATTATTGGTGGGATCTGGTACATTGTCGATCAGACAAAGATGGCCGACCAGAAAGAGTATATCAATTTTGTAATAGTTCCGTAGAAGCCAAATCAGATTTCATGAAGATTATCAGACAAACAATACGAGATAGTGTTCGTAAAATGACATTGCCACAGGGCTCTCAACCAATGAAAAACAATTACACACCGTACGGTGGACAACGCTTACAAAAACTTCCATCAAATGTACGAACGTTGAGTAAATTAAGGAAAGGATGTGGAAAAAGTTCTGATGTGGACAGACATTCAGCAGAATTTGAGGAGAAAATTAATGTATTGGGAGCGGACGATTCTTCGGCGCTCAGGATTCGTAGTCGGACGGTCGGAGATTTAAATGACATGAATGACGACGATGATAACATAATGTGTAAACCTGTTTCATTTGAATCTCAGATATGTCACGATACAAAAAGTTCATGTTCGTCAAATTCTAGTCTTAGTTCTAGCAGCAAAGCGAGTGGATCAGTGGCAAAACTGACACAGGCAAGTGGAAATCCATTAACGTTCTCATCCAATAGCATAGCACAGATTGAAGGTTCTCCTGTGTGGAAACTGCGAAATGAATCCAACATTATGGTCAATAAGGGGCCATATTTATGCGTTCCTAGCAATGCTATTAGTAATAGTTTAGTTAACAGTGCTATTTTGAATAATTCTGTATTAGATCCATCAAAGGAAATTAAGGACACTGAATGTTAG

Transcript

Bpl_scaf_2275-4.3

Protein

Gene family

Gene family	Subfamily
-	-

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00595	PDZ	PDZ domain	Domain	Interproscan
PF00621	RhoGEF	RhoGEF domain	Domain	Interproscan
PF02196	RBD	Raf-like Ras-binding domain	Domain	Interproscan
PF18385	Tiam_CC_Ex	T-lymphoma invasion and metastasis CC-Ex domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000219	Domain	Dbl homology (DH) domain	Interproscan
IPR001478	Domain	PDZ domain	Interproscan
IPR001849	Domain	Pleckstrin homology domain	Interproscan
IPR003116	Domain	Raf-like Ras-binding	Interproscan
IPR011993	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR035899	Homologous_superfamily	Dbl homology (DH) domain superfamily	Interproscan
IPR036034	Homologous_superfamily	PDZ superfamily	Interproscan
IPR040655	Domain	TIAM1, CC-Ex domain	Interproscan
IPR043537	Family	Tiam1/Tiam2/Protein still life	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46001	TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0005085	Molecular Function	guanyl-nucleotide exchange factor activity	Interproscan
GO:0005515	Molecular Function	protein binding	Interproscan
GO:0007165	Biological Process	signal transduction	Interproscan
GO:0007264	Biological Process	small GTPase-mediated signal transduction	Interproscan
GO:0016020	Cellular Component	membrane	Interproscan
GO:0045202	Cellular Component	synapse	Interproscan
GO:0050772	Biological Process	positive regulation of axonogenesis	Interproscan
GO:0090630	Biological Process	activation of GTPase activity	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K05731	TIAM1; T-lymphoma invasion and metastasis-inducing protein 1	-	Ras signaling pathway	ko04014	PMID: 28812709
			Rap1 signaling pathway	ko04015	PMID: 28812709
			cAMP signaling pathway	ko04024	PMID: 28812709
			Tight junction	ko04530	PMID: 28812709
			Regulation of actin cytoskeleton	ko04810	PMID: 28812709
			Chemokine signaling pathway	ko04062	PMID: 28812709
			Proteoglycans in cancer	ko05205	PMID: 28812709

Expression pattern

1. Expression trend for Bpl_scaf_2275-4.3 global RNA-seq network