Gene ID | Annotation | Scaffold | Start | End | Strand |
---|---|---|---|---|---|
Bpl_scaf_21626-2.6 | IKB KINASE | Bpl_scaf_21626 | 215544 | 247264 | + |
CDS | |||||
Bpl_scaf_21626-2.6 | |||||
Transcript |
Bpl_scaf_21626-2.6 |
Protein |
Bpl_scaf_21626-2.6 |
Gene family | Subfamily |
---|---|
- | - |
Pfam accession | Pfam name | Description | Type | Source |
---|---|---|---|---|
PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
PF18397 | IKBKB_SDD | IQBAL scaffold dimerization domain | Domain | Interproscan |
InterPro term | Type | Description | Source |
---|---|---|---|
IPR000719 | Domain | Protein kinase domain | Interproscan |
IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
IPR041185 | Domain | IKBKB, scaffold dimerization domain | Interproscan |
IPR046375 | Homologous_superfamily | IKBKB, scaffold dimerization domain superfamily | Interproscan |
IPR051180 | Family | Inhibitor of nuclear factor kappa-B kinase | Interproscan |
PANTHER term | Description | Source |
---|---|---|
PTHR22969 | IKB KINASE | Interproscan |
GO terms | Category | Description | Source |
---|---|---|---|
GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
GO:0004674 | Molecular Function | protein serine/threonine kinase activity | Interproscan |
GO:0005524 | Molecular Function | ATP binding | Interproscan |
GO:0005737 | Cellular Component | cytoplasm | Interproscan |
GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
GO:0008384 | Molecular Function | IkappaB kinase activity | Interproscan |
GO:0008385 | Cellular Component | IkappaB kinase complex | Interproscan |
GO:0018105 | Biological Process | peptidyl-serine phosphorylation | Interproscan |
GO:0033209 | Biological Process | tumor necrosis factor-mediated signaling pathway | Interproscan |
GO:0045944 | Biological Process | positive regulation of transcription by RNA polymerase II | Interproscan |
GO:0051092 | Biological Process | positive regulation of NF-kappaB transcription factor activity | Interproscan |
KO | Enzyme | Enzyme ID | pathway | mapID | Source |
---|---|---|---|---|---|
K04467 | IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha | EC:2.7.11.10 | Ras signaling pathway | ko04014 | PMID: 28812709 |
MAPK signaling pathway | ko04010 | PMID: 28812709 | |||
NF-kappa B signaling pathway | ko04064 | PMID: 28812709 | |||
TNF signaling pathway | ko04668 | PMID: 28812709 | |||
FoxO signaling pathway | ko04068 | PMID: 28812709 | |||
PI3K-Akt signaling pathway | ko04151 | PMID: 28812709 | |||
mTOR signaling pathway | ko04150 | PMID: 28812709 | |||
Apoptosis | ko04210 | PMID: 28812709 | |||
Toll-like receptor signaling pathway | ko04620 | PMID: 28812709 | |||
NOD-like receptor signaling pathway | ko04621 | PMID: 28812709 | |||
RIG-I-like receptor signaling pathway | ko04622 | PMID: 28812709 | |||
Cytosolic DNA-sensing pathway | ko04623 | PMID: 28812709 | |||
T cell receptor signaling pathway | ko04660 | PMID: 28812709 | |||
Th1 and Th2 cell differentiation | ko04658 | PMID: 28812709 | |||
Th17 cell differentiation | ko04659 | PMID: 28812709 | |||
IL-17 signaling pathway | ko04657 | PMID: 28812709 | |||
B cell receptor signaling pathway | ko04662 | PMID: 28812709 | |||
Chemokine signaling pathway | ko04062 | PMID: 28812709 | |||
Adipocytokine signaling pathway | ko04920 | PMID: 28812709 | |||
Osteoclast differentiation | ko04380 | PMID: 28812709 | |||
Pathways in cancer | ko05200 | PMID: 28812709 | |||
Pancreatic cancer | ko05212 | PMID: 28812709 | |||
Acute myeloid leukemia | ko05221 | PMID: 28812709 | |||
Chronic myeloid leukemia | ko05220 | PMID: 28812709 | |||
Prostate cancer | ko05215 | PMID: 28812709 | |||
Small cell lung cancer | ko05222 | PMID: 28812709 | |||
Fluid shear stress and atherosclerosis | ko05418 | PMID: 28812709 | |||
Epithelial cell signaling in Helicobacter pylori infection | ko05120 | PMID: 28812709 | |||
Shigellosis | ko05131 | PMID: 28812709 | |||
HTLV-I infection | ko05166 | PMID: 28812709 | |||
Measles | ko05162 | PMID: 28812709 | |||
Hepatitis B | ko05161 | PMID: 28812709 | |||
Hepatitis C | ko05160 | PMID: 28812709 | |||
Herpes simplex infection | ko05168 | PMID: 28812709 | |||
Kaposi's sarcoma-associated herpesvirus infection | ko05167 | PMID: 28812709 | |||
Epstein-Barr virus infection | ko05169 | PMID: 28812709 | |||
Human papillomavirus infection | ko05165 | PMID: 28812709 | |||
Toxoplasmosis | ko05145 | PMID: 28812709 | |||
Chagas disease (American trypanosomiasis) | ko05142 | PMID: 28812709 | |||
Antifolate resistance | ko01523 | PMID: 28812709 |
1. Expression trend for Bpl_scaf_21626-2.6 global RNA-seq network |