| Gene ID | Annotation | Scaffold | Start | End | Strand |
|---|---|---|---|---|---|
| Bpl_scaf_10139-15.3 | FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER | Bpl_scaf_10139 | 1443792 | 1497380 | - |
| CDS | |||||
| Bpl_scaf_10139-15.3 | |||||
| Transcript |
| Bpl_scaf_10139-15.3 |
| Protein |
| Bpl_scaf_10139-15.3 |
| Gene family | Subfamily |
|---|---|
| - | - |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00373 | FERM_M | FERM central domain | Domain | Interproscan |
| PF03623 | Focal_AT | Focal adhesion targeting region | Domain | Interproscan |
| PF07714 | PK_Tyr_Ser-Thr | Protein tyrosine and serine/threonine kinase | Domain | Interproscan |
| PF18038 | FERM_N_2 | FERM N-terminal domain | Domain | Interproscan |
| PF21477 | FERM_C_FAK1 | FAK1/PYK2, FERM domain C-lobe | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000299 | Domain | FERM domain | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR001245 | Domain | Serine-threonine/tyrosine-protein kinase, catalytic domain | Interproscan |
| IPR005189 | Domain | Focal adhesion kinase, targeting (FAT) domain | Interproscan |
| IPR008266 | Active_site | Tyrosine-protein kinase, active site | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR014352 | Homologous_superfamily | FERM/acyl-CoA-binding protein superfamily | Interproscan |
| IPR017441 | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR019748 | Domain | FERM central domain | Interproscan |
| IPR019749 | Domain | Band 4.1 domain | Interproscan |
| IPR020635 | Domain | Tyrosine-protein kinase, catalytic domain | Interproscan |
| IPR029071 | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| IPR035963 | Homologous_superfamily | FERM superfamily, second domain | Interproscan |
| IPR036137 | Homologous_superfamily | Focal adhesion kinase, targeting (FAT) domain superfamily | Interproscan |
| IPR041390 | Domain | Focal adhesion kinase, N-terminal | Interproscan |
| IPR041784 | Domain | FAK1/PYK2, FERM domain C-lobe | Interproscan |
| IPR049385 | Domain | FAK1-like, FERM domain C-lobe | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46221 | FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0004713 | Molecular Function | protein tyrosine kinase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0005856 | Cellular Component | cytoskeleton | Interproscan |
| GO:0005925 | Cellular Component | focal adhesion | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0007172 | Biological Process | signal complex assembly | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K05725 | PTK2, FAK; focal adhesion kinase 1 | EC:2.7.10.2 | ErbB signaling pathway | ko04012 | PMID: 28812709 |
| VEGF signaling pathway | ko04370 | PMID: 28812709 | |||
| PI3K-Akt signaling pathway | ko04151 | PMID: 28812709 | |||
| Focal adhesion | ko04510 | PMID: 28812709 | |||
| Regulation of actin cytoskeleton | ko04810 | PMID: 28812709 | |||
| Leukocyte transendothelial migration | ko04670 | PMID: 28812709 | |||
| Chemokine signaling pathway | ko04062 | PMID: 28812709 | |||
| Axon guidance | ko04360 | PMID: 28812709 | |||
| Pathways in cancer | ko05200 | PMID: 28812709 | |||
| Transcriptional misregulation in cancers | ko05202 | PMID: 28812709 | |||
| Proteoglycans in cancer | ko05205 | PMID: 28812709 | |||
| Small cell lung cancer | ko05222 | PMID: 28812709 | |||
| Fluid shear stress and atherosclerosis | ko05418 | PMID: 28812709 | |||
| Bacterial invasion of epithelial cells | ko05100 | PMID: 28812709 | |||
| Human papillomavirus infection | ko05165 | PMID: 28812709 | |||
| Amoebiasis | ko05146 | PMID: 28812709 | |||
| Endocrine resistance | ko01522 | PMID: 28812709 |
| 1. Expression trend for Bpl_scaf_10139-15.3 global RNA-seq network |