Genomic Location: chr8:22269889...22278696
NR annotation: XP_020914597.1, methylenetetrahydrofolate reductase isoform X3 [Exaiptasia diaphana]
| CDS | |
| gene27384.t1 | |
| Transcript |
| gene27384.t1 |
| Protein |
| gene27384.t1 |
| Uniprot term | Description |
|---|---|
| P42898 | Methylenetetrahydrofolate reductase (NADPH) OS=Homo sapiens OX=9606 GN=MTHFR PE=1 SV=3 |
| Q60HE5 | Methylenetetrahydrofolate reductase (NADPH) OS=Macaca fascicularis OX=9541 GN=MTHFR PE=2 SV=1 |
| Q9WU20 | Methylenetetrahydrofolate reductase (NADPH) OS=Mus musculus OX=10090 GN=Mthfr PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02219 | MTHFR | Methylenetetrahydrofolate reductase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR003171 | Family | Methylenetetrahydrofolate reductase-like | Interproscan |
| IPR029041 | Homologous_superfamily | FAD-linked oxidoreductase-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45754 | METHYLENETETRAHYDROFOLATE REDUCTASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004489 | Molecular Function | methylenetetrahydrofolate reductase (NAD(P)H) activity | Interproscan |
| GO:0006555 | Biological Process | methionine metabolic process | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0009086 | Biological Process | methionine biosynthetic process | Interproscan |
| GO:0035999 | Biological Process | tetrahydrofolate interconversion | Interproscan |
| GO:0071949 | Molecular Function | FAD binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K25004 | MTHFR; methylenetetrahydrofolate reductase (NADPH) | EC:1.5.1.53 | Antifolate resistance | ko01523 | deepkoala |