Genomic Location: chr8:21968305...21983295
NR annotation: XP_031554443.1, phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like [Actinia tenebrosa]
| CDS | |
| gene27352.t1 | |
| Transcript |
| gene27352.t1 |
| Protein |
| gene27352.t1 |
| Uniprot term | Description |
|---|---|
| Q8BTI9 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform OS=Mus musculus OX=10090 GN=Pik3cb PE=1 SV=2 |
| P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform OS=Homo sapiens OX=9606 GN=PIK3CB PE=1 SV=1 |
| Q9Z1L0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform OS=Rattus norvegicus OX=10116 GN=Pik3cb PE=2 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00454 | PI3_PI4_kinase | Phosphatidylinositol 3- and 4-kinase | Family | Interproscan |
| PF02192 | PI3K_p85B | PI3-kinase family, p85-binding domain | Family | Interproscan |
| PF00613 | PI3Ka | Phosphoinositide 3-kinase family, accessory domain (PIK domain) | Repeat | Interproscan |
| PF00794 | PI3K_rbd | PI3-kinase family, ras-binding domain | Domain | Interproscan |
| PF00792 | PI3K_C2 | Phosphoinositide 3-kinase C2 | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036940 | Homologous_superfamily | Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily | Interproscan |
| IPR003113 | Domain | Phosphatidylinositol 3-kinase, adaptor-binding domain | Interproscan |
| IPR001263 | Domain | Phosphoinositide 3-kinase, accessory (PIK) domain | Interproscan |
| IPR002420 | Domain | C2 phosphatidylinositol 3-kinase-type domain | Interproscan |
| IPR016024 | Homologous_superfamily | Armadillo-type fold | Interproscan |
| IPR000341 | Domain | Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR015433 | Family | Phosphatidylinositol kinase | Interproscan |
| IPR018936 | Conserved_site | Phosphatidylinositol 3/4-kinase, conserved site | Interproscan |
| IPR000403 | Domain | Phosphatidylinositol 3-/4-kinase, catalytic domain | Interproscan |
| IPR035892 | Homologous_superfamily | C2 domain superfamily | Interproscan |
| IPR042236 | Homologous_superfamily | Phosphoinositide 3-kinase, accessory (PIK) domain superfamily | Interproscan |
| IPR029071 | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10048 | PHOSPHATIDYLINOSITOL KINASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0005942 | Cellular Component | phosphatidylinositol 3-kinase complex | Interproscan |
| GO:0014065 | Biological Process | obsolete phosphatidylinositol 3-kinase signaling | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0016303 | Molecular Function | 1-phosphatidylinositol-3-kinase activity | Interproscan |
| GO:0016477 | Biological Process | cell migration | Interproscan |
| GO:0035005 | Molecular Function | 1-phosphatidylinositol-4-phosphate 3-kinase activity | Interproscan |
| GO:0036092 | Biological Process | phosphatidylinositol-3-phosphate biosynthetic process | Interproscan |
| GO:0046854 | Biological Process | phosphatidylinositol phosphate biosynthetic process | Interproscan |
| GO:0048015 | Biological Process | phosphatidylinositol-mediated signaling | Interproscan |
| GO:0052742 | Molecular Function | phosphatidylinositol kinase activity | Interproscan |
| GO:0016301 | Molecular Function | kinase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00922 | PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta | EC:2.7.1.153 | Membrane trafficking | ko04131 | deepkoala |