Genomic Location: chr7:16641951...16646861
NR annotation: XP_020912274.2, DNA-(apurinic or apyrimidinic site) lyase 2 [Exaiptasia diaphana]
| CDS | |
| gene24775.t1 | |
| Transcript |
| gene24775.t1 |
| Protein |
| gene24775.t1 |
| Uniprot term | Description |
|---|---|
| Q6DDT4 | DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Xenopus laevis OX=8355 GN=apex2.L PE=1 SV=1 |
| Q68G58 | DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Mus musculus OX=10090 GN=Apex2 PE=1 SV=1 |
| Q5E9N9 | DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Bos taurus OX=9913 GN=APEX2 PE=2 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF03372 | Exo_endo_phos | Endonuclease/Exonuclease/phosphatase family | Domain | Interproscan |
| PF06839 | zf-GRF | GRF zinc finger | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036691 | Homologous_superfamily | Endonuclease/exonuclease/phosphatase superfamily | Interproscan |
| IPR005135 | Domain | Endonuclease/exonuclease/phosphatase | Interproscan |
| IPR004808 | Family | AP endonuclease 1 | Interproscan |
| IPR010666 | Domain | Zinc finger, GRF-type | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22748 | AP ENDONUCLEASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003824 | Molecular Function | catalytic activity | Interproscan |
| GO:0003906 | Molecular Function | DNA-(apurinic or apyrimidinic site) endonuclease activity | Interproscan |
| GO:0004518 | Molecular Function | nuclease activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0006281 | Biological Process | DNA repair | Interproscan |
| GO:0006284 | Biological Process | base-excision repair | Interproscan |
| GO:0008081 | Molecular Function | phosphoric diester hydrolase activity | Interproscan |
| GO:0008311 | Molecular Function | double-stranded DNA 3'-5' DNA exonuclease activity | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K10772 | APEX2; AP endonuclease 2 | EC:3.1.11.2 | DNA repair and recombination proteins | ko03400 | deepkoala |