Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr6:6649747...6667158
NR annotation: XP_020894054.1, cleavage and polyadenylation specificity factor subunit 3 [Exaiptasia diaphana]
| CDS | |
| gene21328.t1 | |
| Transcript |
| gene21328.t1 |
| Protein |
| gene21328.t1 |
| Uniprot term | Description |
|---|---|
| P79101 | Cleavage and polyadenylation specificity factor subunit 3 OS=Bos taurus OX=9913 GN=CPSF3 PE=1 SV=1 |
| Q9UKF6 | Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 |
| Q9QXK7 | Cleavage and polyadenylation specificity factor subunit 3 OS=Mus musculus OX=10090 GN=Cpsf3 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF16661 | Lactamase_B_6 | Metallo-beta-lactamase superfamily domain | Domain | Interproscan |
| PF07521 | RMMBL | Zn-dependent metallo-hydrolase RNA specificity domain | Motif | Interproscan |
| PF10996 | Beta-Casp | Beta-Casp domain | Domain | Interproscan |
| PF11718 | CPSF73-100_C | Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036866 | Homologous_superfamily | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like | Interproscan |
| IPR001279 | Domain | Metallo-beta-lactamase | Interproscan |
| IPR011108 | Domain | Zn-dependent metallo-hydrolase, RNA specificity domain | Interproscan |
| IPR022712 | Domain | Beta-Casp domain | Interproscan |
| IPR050698 | Family | RNA Processing Metallo-Beta-Lactamase Domain-Containing Protein | Interproscan |
| IPR021718 | Domain | Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11203 | CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003723 | Molecular Function | RNA binding | Interproscan |
| GO:0004521 | Molecular Function | RNA endonuclease activity | Interproscan |
| GO:0004534 | Molecular Function | 5'-3' RNA exonuclease activity | Interproscan |
| GO:0005847 | Cellular Component | mRNA cleavage and polyadenylation specificity factor complex | Interproscan |
| GO:0006378 | Biological Process | obsolete mRNA polyadenylation | Interproscan |
| GO:0006398 | Biological Process | mRNA 3'-end processing by stem-loop binding and cleavage | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K14403 | CPSF3, YSH1; cleavage and polyadenylation specificity factor subunit 3 | EC:3.1.27.- | Messenger RNA biogenesis | ko03019 | deepkoala |