Genomic Location: chr5:48829564...48869808
NR annotation: XP_031566695.1, methionine synthase-like [Actinia tenebrosa]
| CDS | |
| gene20538.t1 | |
| Transcript |
| gene20538.t1 |
| Protein |
| gene20538.t1 |
| Uniprot term | Description |
|---|---|
| Q4JIJ3 | Methionine synthase OS=Bos taurus OX=9913 GN=MTR PE=2 SV=1 |
| Q9Z2Q4 | Methionine synthase OS=Rattus norvegicus OX=10116 GN=Mtr PE=1 SV=1 |
| Q99707 | Methionine synthase OS=Homo sapiens OX=9606 GN=MTR PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02965 | Met_synt_B12 | Vitamin B12 dependent methionine synthase, activation domain | Domain | Interproscan |
| PF02607 | B12-binding_2 | B12 binding domain | Domain | Interproscan |
| PF02310 | B12-binding | B12 binding domain | Domain | Interproscan |
| PF02574 | S-methyl_trans | Homocysteine S-methyltransferase | Family | Interproscan |
| PF00809 | Pterin_bind | Pterin binding enzyme | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR004223 | Domain | Vitamin B12-dependent methionine synthase, activation domain | Interproscan |
| IPR036594 | Homologous_superfamily | Methionine synthase domain | Interproscan |
| IPR037010 | Homologous_superfamily | Vitamin B12-dependent methionine synthase, activation domain superfamily | Interproscan |
| IPR036724 | Homologous_superfamily | Cobalamin-binding domain superfamily | Interproscan |
| IPR003759 | Domain | Cobalamin (vitamin B12)-binding module, cap domain | Interproscan |
| IPR000489 | Domain | Pterin-binding domain | Interproscan |
| IPR011005 | Homologous_superfamily | Dihydropteroate synthase-like superfamily | Interproscan |
| IPR036589 | Homologous_superfamily | Homocysteine-binding domain superfamily | Interproscan |
| IPR011822 | Family | Cobalamin-dependent methionine synthase | Interproscan |
| IPR050554 | Family | Methionine Synthase/Corrinoid | Interproscan |
| IPR006158 | Domain | Cobalamin (vitamin B12)-binding domain | Interproscan |
| IPR003726 | Domain | Homocysteine-binding domain | Interproscan |
| IPR033706 | Domain | Methionine synthase, B12-binding domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45833 | METHIONINE SYNTHASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0008705 | Molecular Function | methionine synthase activity | Interproscan |
| GO:0009086 | Biological Process | methionine biosynthetic process | Interproscan |
| GO:0031419 | Molecular Function | cobalamin binding | Interproscan |
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| GO:0042558 | Biological Process | pteridine-containing compound metabolic process | Interproscan |
| GO:0044237 | Biological Process | obsolete cellular metabolic process | Interproscan |
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0046653 | Biological Process | tetrahydrofolate metabolic process | Interproscan |
| GO:0050667 | Biological Process | homocysteine metabolic process | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00548 | metH, MTR; 5-methyltetrahydrofolate--homocysteine methyltransferase | EC:2.1.1.13 | Cobalamin transport and metabolism | ko04980 | deepkoala |