Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr4:32091003...32104203
NR annotation: KXJ19421.1, Valine--tRNA ligase [Exaiptasia diaphana]
| CDS | |
| gene15520.t1 | |
| Transcript |
| gene15520.t1 |
| Protein |
| gene15520.t1 |
| Uniprot term | Description |
|---|---|
| Q9Z1Q9 | Valine--tRNA ligase OS=Mus musculus OX=10090 GN=Vars1 PE=1 SV=1 |
| Q04462 | Valine--tRNA ligase OS=Rattus norvegicus OX=10116 GN=Vars1 PE=2 SV=2 |
| P26640 | Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00133 | tRNA-synt_1 | tRNA synthetases class I (I, L, M and V) | Domain | Interproscan |
| PF08264 | Anticodon_1 | Anticodon-binding domain of tRNA ligase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002300 | Domain | Aminoacyl-tRNA synthetase, class Ia | Interproscan |
| IPR009008 | Homologous_superfamily | Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain | Interproscan |
| IPR037118 | Homologous_superfamily | Valyl-tRNA synthetase, tRNA-binding arm superfamily | Interproscan |
| IPR033705 | Domain | Valyl tRNA synthetase, anticodon-binding domain | Interproscan |
| IPR014729 | Homologous_superfamily | Rossmann-like alpha/beta/alpha sandwich fold | Interproscan |
| IPR002303 | Family | Valine-tRNA ligase | Interproscan |
| IPR001412 | Conserved_site | Aminoacyl-tRNA synthetase, class I, conserved site | Interproscan |
| IPR013155 | Domain | Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding | Interproscan |
| IPR009080 | Homologous_superfamily | Aminoacyl-tRNA synthetase, class Ia, anticodon-binding | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11946 | VALYL-TRNA SYNTHETASES | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0000166 | Molecular Function | nucleotide binding | Interproscan |
| GO:0004812 | Molecular Function | aminoacyl-tRNA ligase activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0006418 | Biological Process | tRNA aminoacylation for protein translation | Interproscan |
| GO:0002161 | Molecular Function | aminoacyl-tRNA editing activity | Interproscan |
| GO:0004832 | Molecular Function | valine-tRNA ligase activity | Interproscan |
| GO:0006438 | Biological Process | valyl-tRNA aminoacylation | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K01873 | VARS, valS; valyl-tRNA synthetase | EC:6.1.1.9 | Transfer RNA biogenesis | ko03016 | deepkoala |