Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr4:22299222...22316583
NR annotation: XP_020906782.1, ral guanine nucleotide dissociation stimulator-like 1 [Exaiptasia diaphana]
| CDS | |
| gene14812.t1 | |
| Transcript |
| gene14812.t1 |
| Protein |
| gene14812.t1 |
| Uniprot term | Description |
|---|---|
| Q9NZL6 | Ral guanine nucleotide dissociation stimulator-like 1 OS=Homo sapiens OX=9606 GN=RGL1 PE=1 SV=1 |
| Q60695 | Ral guanine nucleotide dissociation stimulator-like 1 OS=Mus musculus OX=10090 GN=Rgl1 PE=1 SV=2 |
| Q6P112 | Ral guanine nucleotide dissociation stimulator-like 1 OS=Danio rerio OX=7955 GN=rgl1 PE=2 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00617 | RasGEF | RasGEF domain | Family | Interproscan |
| PF00788 | RA | Ras association (RalGDS/AF-6) domain | Domain | Interproscan |
| PF00618 | RasGEF_N | RasGEF N-terminal motif | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001895 | Domain | Ras guanine-nucleotide exchange factors catalytic domain | Interproscan |
| IPR000651 | Domain | Ras-like guanine nucleotide exchange factor, N-terminal | Interproscan |
| IPR029071 | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| IPR000159 | Domain | Ras-associating domain | Interproscan |
| IPR008937 | Family | Ras-like guanine nucleotide exchange factor | Interproscan |
| IPR036964 | Homologous_superfamily | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Interproscan |
| IPR023578 | Homologous_superfamily | Ras guanine nucleotide exchange factor domain superfamily | Interproscan |
| IPR019804 | Conserved_site | Ras guanine-nucleotide exchange factor, conserved site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0007264 | Biological Process | small GTPase-mediated signal transduction | Interproscan |
| GO:0007165 | Biological Process | signal transduction | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0007265 | Biological Process | Ras protein signal transduction | Interproscan |
| GO:0043547 | Biological Process | positive regulation of GTPase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K17635 | RGL1, RGL; ral guanine nucleotide dissociation stimulator-like 1 | - | Ras signaling pathway | ko04014 | deepkoala |