Genomic Location: chr3:32651998...32668904
NR annotation: XP_020911885.1, histone-lysine N-methyltransferase EZH2 [Exaiptasia diaphana]
| CDS | |
| gene11282.t1 | |
| Transcript |
| gene11282.t1 |
| Protein |
| gene11282.t1 |
| Uniprot term | Description |
|---|---|
| Q4V863 | Histone-lysine N-methyltransferase EZH2 OS=Xenopus laevis OX=8355 GN=ezh2-b PE=2 SV=1 |
| Q61188 | Histone-lysine N-methyltransferase EZH2 OS=Mus musculus OX=10090 GN=Ezh2 PE=1 SV=2 |
| Q15910 | Histone-lysine N-methyltransferase EZH2 OS=Homo sapiens OX=9606 GN=EZH2 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21358 | Ezh2_MCSS | Ezh2, MCSS domain | Domain | Interproscan |
| PF18264 | preSET_CXC | CXC domain | Domain | Interproscan |
| PF18118 | PRC2_HTH_1 | Polycomb repressive complex 2 tri-helical domain | Domain | Interproscan |
| PF00856 | SET | SET domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR048358 | Domain | EZH1/2, MCSS domain | Interproscan |
| IPR001214 | Domain | SET domain | Interproscan |
| IPR026489 | Domain | CXC domain | Interproscan |
| IPR033467 | Domain | Tesmin/TSO1-like CXC domain | Interproscan |
| IPR041355 | Domain | Pre-SET CXC domain | Interproscan |
| IPR045318 | Family | Histone-lysine N-methyltransferase EZH1/2-like | Interproscan |
| IPR046341 | Homologous_superfamily | SET domain superfamily | Interproscan |
| IPR041343 | Domain | Polycomb repressive complex 2 subunit EZH1/EZH2, tri-helical domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45747 | HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0003682 | Molecular Function | chromatin binding | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0006338 | Biological Process | chromatin remodeling | Interproscan |
| GO:0031507 | Biological Process | heterochromatin formation | Interproscan |
| GO:0035098 | Cellular Component | ESC/E(Z) complex | Interproscan |
| GO:0042054 | Molecular Function | histone methyltransferase activity | Interproscan |
| GO:0046976 | Molecular Function | histone H3K27 methyltransferase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K11430 | EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 | EC:2.1.1.356 | Chromosome and associated proteins | ko03036 | deepkoala |