Genomic Location: chr3:32330596...32331714
NR annotation: XP_020903381.1, egl nine homolog 1 [Exaiptasia diaphana]
| CDS | |
| gene11257.t1 | |
| Transcript |
| gene11257.t1 |
| Protein |
| gene11257.t1 |
| Uniprot term | Description |
|---|---|
| Q91YE3 | Egl nine homolog 1 OS=Mus musculus OX=10090 GN=Egln1 PE=1 SV=2 |
| P59722 | Egl nine homolog 1 (Fragment) OS=Rattus norvegicus OX=10116 GN=Egln1 PE=2 SV=2 |
| Q9GZT9 | Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13640 | 2OG-FeII_Oxy_3 | 2OG-Fe(II) oxygenase superfamily | Domain | Interproscan |
| PF01753 | zf-MYND | MYND finger | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR051559 | Family | Hypoxia-inducible factor prolyl hydroxylases | Interproscan |
| IPR006620 | Domain | Prolyl 4-hydroxylase, alpha subunit | Interproscan |
| IPR002893 | Domain | Zinc finger, MYND-type | Interproscan |
| IPR005123 | Domain | Oxoglutarate/iron-dependent dioxygenase | Interproscan |
| IPR044862 | Domain | Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12907 | EGL NINE HOMOLOG-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0008198 | Molecular Function | ferrous iron binding | Interproscan |
| GO:0031543 | Molecular Function | peptidyl-proline dioxygenase activity | Interproscan |
| GO:0071456 | Biological Process | cellular response to hypoxia | Interproscan |
| GO:0005506 | Molecular Function | iron ion binding | Interproscan |
| GO:0016705 | Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Interproscan |
| GO:0031418 | Molecular Function | L-ascorbic acid binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K09592 | EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase | EC:1.14.11.29 | Renal cell carcinoma | ko05211 | deepkoala |