Genomic Location: chr3:26752294...26756012
NR annotation: XP_031556744.1, dihydrofolate reductase-like isoform X1 [Actinia tenebrosa]
| CDS | |
| gene10841.t1 | |
| Transcript |
| gene10841.t1 |
| Protein |
| gene10841.t1 |
| Uniprot term | Description |
|---|---|
| Q920D2 | Dihydrofolate reductase OS=Rattus norvegicus OX=10116 GN=Dhfr PE=1 SV=3 |
| P00375 | Dihydrofolate reductase OS=Mus musculus OX=10090 GN=Dhfr PE=1 SV=3 |
| P00374 | Dihydrofolate reductase OS=Homo sapiens OX=9606 GN=DHFR PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00186 | DHFR_1 | Dihydrofolate reductase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR024072 | Homologous_superfamily | Dihydrofolate reductase-like domain superfamily | Interproscan |
| IPR001796 | Domain | Dihydrofolate reductase domain | Interproscan |
| IPR017925 | Conserved_site | Dihydrofolate reductase conserved site | Interproscan |
| IPR012259 | Family | Dihydrofolate reductase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR48069 | DIHYDROFOLATE REDUCTASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004146 | Molecular Function | dihydrofolate reductase activity | Interproscan |
| GO:0046654 | Biological Process | tetrahydrofolate biosynthetic process | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0046452 | Biological Process | dihydrofolate metabolic process | Interproscan |
| GO:0046655 | Biological Process | folic acid metabolic process | Interproscan |
| GO:0050661 | Molecular Function | NADP binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00287 | DHFR, folA; dihydrofolate reductase | EC:1.5.1.3 | Antifolate resistance | ko01523 | deepkoala |