Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr2:32942796...32955597
NR annotation: XP_020893855.1, ARF GTPase-activating protein GIT2 [Exaiptasia diaphana]
| CDS | |
| gene06349.t1 | |
| Transcript |
| gene06349.t1 |
| Protein |
| gene06349.t1 |
| Uniprot term | Description |
|---|---|
| Q14161 | ARF GTPase-activating protein GIT2 OS=Homo sapiens OX=9606 GN=GIT2 PE=1 SV=2 |
| Q66H91 | ARF GTPase-activating protein GIT2 OS=Rattus norvegicus OX=10116 GN=Git2 PE=1 SV=1 |
| Q9Y2X7 | ARF GTPase-activating protein GIT1 OS=Homo sapiens OX=9606 GN=GIT1 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01412 | ArfGap | Putative GTPase activating protein for Arf | Domain | Interproscan |
| PF12796 | Ank_2 | Ankyrin repeats (3 copies) | Repeat | Interproscan |
| PF16559 | GIT_CC | GIT coiled-coil Rho guanine nucleotide exchange factor | Coiled-coil | Interproscan |
| PF12205 | GIT1_C | G protein-coupled receptor kinase-interacting protein 1 C term | Domain | Interproscan |
| PF08518 | GIT_SHD | Spa2 homology domain (SHD) of GIT | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002110 | Repeat | Ankyrin repeat | Interproscan |
| IPR001164 | Domain | Arf GTPase activating protein | Interproscan |
| IPR013724 | Domain | GIT, Spa2 homology (SHD) domain | Interproscan |
| IPR036770 | Homologous_superfamily | Ankyrin repeat-containing domain superfamily | Interproscan |
| IPR032352 | Domain | Arf GTPase-activating protein GIT1/2, coiled-coil domain | Interproscan |
| IPR047161 | Family | ARF GTPase-activating protein Git-like | Interproscan |
| IPR022018 | Domain | ARF GTPase-activating protein GIT1, C-terminal | Interproscan |
| IPR038508 | Homologous_superfamily | ArfGAP domain superfamily | Interproscan |
| IPR037278 | Homologous_superfamily | ARFGAP/RecO-like zinc finger | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46097 | G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005096 | Molecular Function | GTPase activator activity | Interproscan |
| GO:0007420 | Biological Process | brain development | Interproscan |
| GO:0008277 | Biological Process | regulation of G protein-coupled receptor signaling pathway | Interproscan |
| GO:0031267 | Molecular Function | small GTPase binding | Interproscan |
| GO:0032012 | Biological Process | regulation of ARF protein signal transduction | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K12487 | GIT2; G protein-coupled receptor kinase interactor 2 | - | Membrane trafficking | ko04131 | deepkoala |