Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr2:31601786...31613149
NR annotation: XP_020914675.1, TNF receptor-associated factor 4 isoform X1 [Exaiptasia diaphana]
| CDS | |
| gene06223.t2 | |
| Transcript |
| gene06223.t2 |
| Protein |
| gene06223.t2 |
| Uniprot term | Description |
|---|---|
| Q61382 | TNF receptor-associated factor 4 OS=Mus musculus OX=10090 GN=Traf4 PE=1 SV=2 |
| Q9BUZ4 | TNF receptor-associated factor 4 OS=Homo sapiens OX=9606 GN=TRAF4 PE=1 SV=1 |
| P39429 | TNF receptor-associated factor 2 OS=Mus musculus OX=10090 GN=Traf2 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21355 | TRAF-mep_MATH | TRAF/meprin, MATH domain | Domain | Interproscan |
| PF02176 | zf-TRAF | TRAF-type zinc finger | Family | Interproscan |
| PF00097 | zf-C3HC4 | Zinc finger, C3HC4 type (RING finger) | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR013083 | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR001293 | Domain | Zinc finger, TRAF-type | Interproscan |
| IPR049342 | Domain | TRAF1-6/MEP1A/B-like, MATH domain | Interproscan |
| IPR002083 | Domain | MATH/TRAF domain | Interproscan |
| IPR001841 | Domain | Zinc finger, RING-type | Interproscan |
| IPR008974 | Homologous_superfamily | TRAF-like | Interproscan |
| IPR017907 | Conserved_site | Zinc finger, RING-type, conserved site | Interproscan |
| IPR012227 | Family | TNF receptor-associated factor TRAF, metazoa | Interproscan |
| IPR018957 | Domain | Zinc finger, C3HC4 RING-type | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10131 | TNF RECEPTOR ASSOCIATED FACTOR | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0008270 | Molecular Function | zinc ion binding | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0033209 | Biological Process | tumor necrosis factor-mediated signaling pathway | Interproscan |
| GO:0070534 | Biological Process | protein K63-linked ubiquitination | Interproscan |
| GO:0007165 | Biological Process | signal transduction | Interproscan |
| GO:0042981 | Biological Process | regulation of apoptotic process | Interproscan |
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K09848 | TRAF4; TNF receptor-associated factor 4 | - | Small cell lung cancer | ko05222 | deepkoala |