Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr2:30364450...30371701
NR annotation: XP_020910019.1, protein cereblon [Exaiptasia diaphana]
| CDS | |
| gene06112.t1 | |
| Transcript |
| gene06112.t1 |
| Protein |
| gene06112.t1 |
| Uniprot term | Description |
|---|---|
| Q96SW2 | Protein cereblon OS=Homo sapiens OX=9606 GN=CRBN PE=1 SV=1 |
| Q5R6Y2 | Protein cereblon OS=Pongo abelii OX=9601 GN=CRBN PE=2 SV=1 |
| Q56AP7 | Protein cereblon OS=Rattus norvegicus OX=10116 GN=Crbn PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF03226 | Yippee-Mis18 | Yippee zinc-binding/DNA-binding /Mis18, centromere assembly | Domain | Interproscan |
| PF02190 | LON_substr_bdg | ATP-dependent protease La (LON) substrate-binding domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR004910 | Domain | Yippee/Mis18/Cereblon | Interproscan |
| IPR003111 | Domain | Lon protease, N-terminal domain | Interproscan |
| IPR015947 | Homologous_superfamily | PUA-like superfamily | Interproscan |
| IPR034750 | Domain | CULT domain | Interproscan |
| IPR046336 | Homologous_superfamily | Lon protease, N-terminal domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR14255 | CEREBLON | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0016567 | Biological Process | protein ubiquitination | Interproscan |
| GO:0031464 | Cellular Component | Cul4A-RING E3 ubiquitin ligase complex | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K11793 | CRBN; cereblon | - | Ubiquitin system | ko04121 | deepkoala |