Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr2:29921267...29930510
NR annotation: XP_031549865.1, myotubularin-related protein 6-like [Actinia tenebrosa]
| CDS | |
| gene06066.t1 | |
| Transcript |
| gene06066.t1 |
| Protein |
| gene06066.t1 |
| Uniprot term | Description |
|---|---|
| Q9Y217 | Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6 OS=Homo sapiens OX=9606 GN=MTMR6 PE=1 SV=3 |
| Q5F452 | Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR8 OS=Gallus gallus OX=9031 GN=MTMR8 PE=2 SV=1 |
| Q9Y216 | Phosphatidylinositol-3-phosphate phosphatase MTMR7 OS=Homo sapiens OX=9606 GN=MTMR7 PE=1 SV=3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01363 | FYVE | FYVE zinc finger | Domain | Interproscan |
| PF21098 | PH-GRAM_MTMR6-like | GRAM domain-like | Domain | Interproscan |
| PF06602 | Myotub-related | Myotubularin-like phosphatase domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR013083 | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR011011 | Homologous_superfamily | Zinc finger, FYVE/PHD-type | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR003595 | Domain | Protein-tyrosine phosphatase, catalytic | Interproscan |
| IPR029021 | Homologous_superfamily | Protein-tyrosine phosphatase-like | Interproscan |
| IPR000306 | Domain | FYVE zinc finger | Interproscan |
| IPR017455 | Domain | Zinc finger, FYVE-related | Interproscan |
| IPR010569 | Domain | Myotubularin-like, phosphatase domain | Interproscan |
| IPR016130 | Active_site | Protein-tyrosine phosphatase, active site | Interproscan |
| IPR030564 | Family | Myotubularin family | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10807 | MYOTUBULARIN-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| GO:0016311 | Biological Process | dephosphorylation | Interproscan |
| GO:0004438 | Molecular Function | phosphatidylinositol-3-phosphate phosphatase activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0016020 | Cellular Component | membrane | Interproscan |
| GO:0046856 | Biological Process | phosphatidylinositol dephosphorylation | Interproscan |
| GO:0106018 | Molecular Function | phosphatidylinositol-3,5-bisphosphate phosphatase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K18083 | MTMR6_7_8; myotubularin-related protein 6/7/8 | EC:3.1.3.64 EC:3.1.3.95 | Protein phosphatases and associated proteins | ko01009 | deepkoala |