Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr2:28688983...28707080
NR annotation: XP_020911765.1, serine/threonine-protein phosphatase with EF-hands 2 isoform X1 [Exaiptasia diaphana]
| CDS | |
| gene05937.t1 | |
| Transcript |
| gene05937.t1 |
| Protein |
| gene05937.t1 |
| Uniprot term | Description |
|---|---|
| G5EBX9 | Serine/threonine-protein phosphatase with EF-hands pef-1 OS=Caenorhabditis elegans OX=6239 GN=pef-1 PE=1 SV=1 |
| O14830 | Serine/threonine-protein phosphatase with EF-hands 2 OS=Homo sapiens OX=9606 GN=PPEF2 PE=1 SV=2 |
| O35385 | Serine/threonine-protein phosphatase with EF-hands 2 OS=Mus musculus OX=10090 GN=Ppef2 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00149 | Metallophos | Calcineurin-like phosphoesterase | Domain | Interproscan |
| PF13499 | EF-hand_7 | EF-hand domain pair | Domain | Interproscan |
| PF08321 | PPP5 | PPP5 TPR repeat region | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR018247 | Binding_site | EF-Hand 1, calcium-binding site | Interproscan |
| IPR002048 | Domain | EF-hand domain | Interproscan |
| IPR004843 | Domain | Calcineurin-like phosphoesterase domain, ApaH type | Interproscan |
| IPR006186 | Domain | Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase | Interproscan |
| IPR011992 | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR013235 | Domain | PPP domain | Interproscan |
| IPR029052 | Homologous_superfamily | Metallo-dependent phosphatase-like | Interproscan |
| IPR012008 | Family | Serine/threonine-protein phosphatase with EF-hands | Interproscan |
| IPR051134 | Family | Protein Phosphatase PPP | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45668 | SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005509 | Molecular Function | calcium ion binding | Interproscan |
| GO:0016787 | Molecular Function | hydrolase activity | Interproscan |
| GO:0004721 | Molecular Function | phosphoprotein phosphatase activity | Interproscan |
| GO:0005506 | Molecular Function | iron ion binding | Interproscan |
| GO:0030145 | Molecular Function | manganese ion binding | Interproscan |
| GO:0050906 | Biological Process | detection of stimulus involved in sensory perception | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K13807 | PPEF, PPP7C; serine/threonine-protein phosphatase with EF-hands | EC:3.1.3.16 | Protein phosphatases and associated proteins | ko01009 | deepkoala |