Genomic Location: chr1:50106684...50144489
NR annotation: XP_020916062.1, ras GTPase-activating-like protein IQGAP1 isoform X2 [Exaiptasia diaphana]
| CDS | |
| gene03278.t2 | |
| Transcript |
| gene03278.t2 |
| Protein |
| gene03278.t2 |
| Uniprot term | Description |
|---|---|
| Q9JKF1 | Ras GTPase-activating-like protein IQGAP1 OS=Mus musculus OX=10090 GN=Iqgap1 PE=1 SV=2 |
| P46940 | Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 |
| Q13576 | Ras GTPase-activating-like protein IQGAP2 OS=Homo sapiens OX=9606 GN=IQGAP2 PE=1 SV=4 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00616 | RasGAP | GTPase-activator protein for Ras-like GTPase | Family | Interproscan |
| PF13516 | LRR_6 | Leucine Rich repeat | Repeat | Interproscan |
| PF00612 | IQ | IQ calmodulin-binding motif | Motif | Interproscan |
| PF03836 | RasGAP_C | RasGAP C-terminus | Family | Interproscan |
| PF13499 | EF-hand_7 | EF-hand domain pair | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011992 | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR001936 | Domain | Ras GTPase-activating domain | Interproscan |
| IPR023152 | Conserved_site | Ras GTPase-activating protein, conserved site | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR018247 | Binding_site | EF-Hand 1, calcium-binding site | Interproscan |
| IPR001202 | Domain | WW domain | Interproscan |
| IPR032675 | Homologous_superfamily | Leucine-rich repeat domain superfamily | Interproscan |
| IPR001611 | Repeat | Leucine-rich repeat | Interproscan |
| IPR000048 | Binding_site | IQ motif, EF-hand binding site | Interproscan |
| IPR002048 | Domain | EF-hand domain | Interproscan |
| IPR008936 | Homologous_superfamily | Rho GTPase activation protein | Interproscan |
| IPR036020 | Homologous_superfamily | WW domain superfamily | Interproscan |
| IPR000593 | Domain | RasGAP protein, C-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR14149 | RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0043087 | Biological Process | regulation of GTPase activity | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005509 | Molecular Function | calcium ion binding | Interproscan |
| GO:0005096 | Molecular Function | GTPase activator activity | Interproscan |
| GO:0005516 | Molecular Function | calmodulin binding | Interproscan |
| GO:0005938 | Cellular Component | cell cortex | Interproscan |
| GO:0051015 | Molecular Function | actin filament binding | Interproscan |
| GO:1903479 | Biological Process | mitotic actomyosin contractile ring assembly actin filament organization | Interproscan |