Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr_1:12890194...12901726
NR annotation: KXJ27979.1, Ras guanyl-releasing protein 3 [Exaiptasia diaphana]
| CDS | |
| alvinactis_v1_g760 | |
| Transcript |
| alvinactis_v1_g760 |
| Protein |
| alvinactis_v1_g760 |
| Uniprot term | Description |
|---|---|
| Q8IV61 | Ras guanyl-releasing protein 3 OS=Homo sapiens OX=9606 GN=RASGRP3 PE=1 SV=1 |
| Q6NTL4 | RAS guanyl-releasing protein 1 OS=Xenopus laevis OX=8355 GN=rasgrp1 PE=2 SV=1 |
| Q9R1K8 | RAS guanyl-releasing protein 1 OS=Rattus norvegicus OX=10116 GN=Rasgrp1 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00130 | C1_1 | Phorbol esters/diacylglycerol binding domain (C1 domain) | Domain | Interproscan |
| PF00618 | RasGEF_N | RasGEF N-terminal motif | Domain | Interproscan |
| PF13202 | EF-hand_5 | EF hand | Domain | Interproscan |
| PF00617 | RasGEF | RasGEF domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002048 | Domain | EF-hand domain | Interproscan |
| IPR011992 | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR002219 | Domain | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Interproscan |
| IPR018247 | Binding_site | EF-Hand 1, calcium-binding site | Interproscan |
| IPR001895 | Domain | Ras guanine-nucleotide exchange factors catalytic domain | Interproscan |
| IPR023578 | Homologous_superfamily | Ras guanine nucleotide exchange factor domain superfamily | Interproscan |
| IPR000651 | Domain | Ras-like guanine nucleotide exchange factor, N-terminal | Interproscan |
| IPR008937 | Family | Ras-like guanine nucleotide exchange factor | Interproscan |
| IPR036964 | Homologous_superfamily | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Interproscan |
| IPR046349 | Homologous_superfamily | C1-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005509 | Molecular Function | calcium ion binding | Interproscan |
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0007264 | Biological Process | small GTPase-mediated signal transduction | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0007265 | Biological Process | Ras protein signal transduction | Interproscan |
| GO:0043547 | Biological Process | positive regulation of GTPase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K12362 | RASGRP3; RAS guanyl-releasing protein 3 | - | Domain-containing proteins not elsewhere classified | ko04990 | deepkoala |