Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr_1:12410053...12417442
NR annotation: XP_020917418.1, 3-hydroxyisobutyrate dehydrogenase, mitochondrial [Exaiptasia diaphana]
| CDS | |
| alvinactis_v1_g730 | |
| Transcript |
| alvinactis_v1_g730 |
| Protein |
| alvinactis_v1_g730 |
| Uniprot term | Description |
|---|---|
| Q99L13 | 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Hibadh PE=1 SV=1 |
| P29266 | 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Rattus norvegicus OX=10116 GN=Hibadh PE=1 SV=3 |
| P31937 | 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HIBADH PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21166 | LSM12_LSM | LSM12, LSM domain | Domain | Interproscan |
| PF09793 | AD | Anticodon-binding domain | Domain | Interproscan |
| PF03446 | NAD_binding_2 | NAD binding domain of 6-phosphogluconate dehydrogenase | Domain | Interproscan |
| PF14833 | NAD_binding_11 | NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR047574 | Domain | AD domain | Interproscan |
| IPR011548 | Family | 3-hydroxyisobutyrate dehydrogenase | Interproscan |
| IPR048478 | Domain | LSM12, LSM domain | Interproscan |
| IPR036291 | Homologous_superfamily | NAD(P)-binding domain superfamily | Interproscan |
| IPR013328 | Homologous_superfamily | 6-phosphogluconate dehydrogenase, domain 2 | Interproscan |
| IPR019181 | Domain | LSM12, anticodon-binding domain | Interproscan |
| IPR006115 | Domain | 6-phosphogluconate dehydrogenase, NADP-binding | Interproscan |
| IPR029154 | Domain | 3-hydroxyisobutyrate dehydrogenase-like, NAD-binding domain | Interproscan |
| IPR008927 | Homologous_superfamily | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily | Interproscan |
| IPR002204 | Conserved_site | 3-hydroxyisobutyrate dehydrogenase-related, conserved site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22981 | 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0008442 | Molecular Function | 3-hydroxyisobutyrate dehydrogenase activity | Interproscan |
| GO:0051287 | Molecular Function | NAD binding | Interproscan |
| GO:0050661 | Molecular Function | NADP binding | Interproscan |
| GO:0016491 | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0006574 | Biological Process | valine catabolic process | Interproscan |
| GO:0016616 | Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Interproscan |