Genomic Location: chr_2:36609961...36620603
NR annotation: XP_020914146.1, sestrin-1 [Exaiptasia diaphana]
| CDS | |
| alvinactis_v1_g5142 | |
| Transcript |
| alvinactis_v1_g5142 |
| Protein |
| alvinactis_v1_g5142 |
| Uniprot term | Description |
|---|---|
| Q4R6P7 | Sestrin-1 OS=Macaca fascicularis OX=9541 GN=SESN1 PE=2 SV=1 |
| Q9Y6P5 | Sestrin-1 OS=Homo sapiens OX=9606 GN=SESN1 PE=1 SV=2 |
| P58003 | Sestrin-1 OS=Xenopus laevis OX=8355 GN=sesn1 PE=2 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF04636 | PA26 | PA26 p53-induced protein (sestrin) | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR006730 | Family | Sestrin | Interproscan |
| IPR029032 | Homologous_superfamily | AhpD-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12474 | P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0016239 | Biological Process | positive regulation of macroautophagy | Interproscan |
| GO:0016684 | Molecular Function | oxidoreductase activity, acting on peroxide as acceptor | Interproscan |
| GO:0070728 | Molecular Function | L-leucine binding | Interproscan |
| GO:0071233 | Biological Process | cellular response to L-leucine | Interproscan |
| GO:1901031 | Biological Process | regulation of response to reactive oxygen species | Interproscan |
| GO:1904262 | Biological Process | negative regulation of TORC1 signaling | Interproscan |
| GO:1990253 | Biological Process | cellular response to leucine starvation | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K10141 | SESN1_3; sestrin 1/3 | - | Longevity regulating pathway | ko04211 | deepkoala |