Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr_2:33960369...33981124
NR annotation: XP_028513829.1, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A-like isoform X1 [Exaiptasia diaphana]
| CDS | |
| alvinactis_v1_g4961 | |
| Transcript |
| alvinactis_v1_g4961 |
| Protein |
| alvinactis_v1_g4961 |
| Uniprot term | Description |
|---|---|
| Q8CA95 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A OS=Mus musculus OX=10090 GN=Pde10a PE=1 SV=2 |
| Q9Y233 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A OS=Homo sapiens OX=9606 GN=PDE10A PE=1 SV=2 |
| Q9QYJ6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A OS=Rattus norvegicus OX=10116 GN=Pde10a PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01590 | GAF | GAF domain | Domain | Interproscan |
| PF00233 | PDEase_I | 3'5'-cyclic nucleotide phosphodiesterase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002073 | Domain | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain | Interproscan |
| IPR029016 | Homologous_superfamily | GAF-like domain superfamily | Interproscan |
| IPR023088 | Family | 3'5'-cyclic nucleotide phosphodiesterase | Interproscan |
| IPR036971 | Homologous_superfamily | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily | Interproscan |
| IPR003018 | Domain | GAF domain | Interproscan |
| IPR003607 | Domain | HD/PDEase domain | Interproscan |
| IPR023174 | Conserved_site | 3'5'-cyclic nucleotide phosphodiesterase, conserved site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11347 | CYCLIC NUCLEOTIDE PHOSPHODIESTERASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004114 | Molecular Function | 3',5'-cyclic-nucleotide phosphodiesterase activity | Interproscan |
| GO:0004118 | Molecular Function | 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity | Interproscan |
| GO:0007165 | Biological Process | signal transduction | Interproscan |
| GO:0010754 | Biological Process | negative regulation of cGMP-mediated signaling | Interproscan |
| GO:0008081 | Molecular Function | phosphoric diester hydrolase activity | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |