Genomic Location: chr_1:44816429...44846138
NR annotation: KXJ29821.1, 2-hydroxyacyl-CoA lyase 1 [Exaiptasia diaphana]
| CDS | |
| alvinactis_v1_g2681 | |
| Transcript |
| alvinactis_v1_g2681 |
| Protein |
| alvinactis_v1_g2681 |
| Uniprot term | Description |
|---|---|
| Q9QXE0 | 2-hydroxyacyl-CoA lyase 1 OS=Mus musculus OX=10090 GN=Hacl1 PE=1 SV=2 |
| Q8CHM7 | 2-hydroxyacyl-CoA lyase 1 OS=Rattus norvegicus OX=10116 GN=Hacl1 PE=1 SV=1 |
| Q9UJ83 | 2-hydroxyacyl-CoA lyase 1 OS=Homo sapiens OX=9606 GN=HACL1 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00205 | TPP_enzyme_M | Thiamine pyrophosphate enzyme, central domain | Domain | Interproscan |
| PF02776 | TPP_enzyme_N | Thiamine pyrophosphate enzyme, N-terminal TPP binding domain | Domain | Interproscan |
| PF02775 | TPP_enzyme_C | Thiamine pyrophosphate enzyme, C-terminal TPP binding domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR029035 | Homologous_superfamily | DHS-like NAD/FAD-binding domain superfamily | Interproscan |
| IPR012000 | Domain | Thiamine pyrophosphate enzyme, central domain | Interproscan |
| IPR029061 | Homologous_superfamily | Thiamin diphosphate-binding fold | Interproscan |
| IPR012001 | Domain | Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain | Interproscan |
| IPR045025 | Family | TPP-binding domain containing protein HACL1-like | Interproscan |
| IPR011766 | Domain | Thiamine pyrophosphate enzyme, TPP-binding | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43710 | 2-HYDROXYACYL-COA LYASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0000287 | Molecular Function | magnesium ion binding | Interproscan |
| GO:0030976 | Molecular Function | thiamine pyrophosphate binding | Interproscan |
| GO:0001561 | Biological Process | fatty acid alpha-oxidation | Interproscan |
| GO:0005777 | Cellular Component | peroxisome | Interproscan |
| GO:0003824 | Molecular Function | catalytic activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K12261 | HACL1; 2-hydroxyacyl-CoA lyase | EC:4.1.2.63 | Peroxisome | ko04146 | deepkoala |