Genomic Location: chr_14:5716585...5729896
NR annotation: XP_020898151.1, delta-1-pyrroline-5-carboxylate synthase isoform X2 [Exaiptasia diaphana]
| CDS | |
| alvinactis_v1_g26428 | |
| Transcript |
| alvinactis_v1_g26428 |
| Protein |
| alvinactis_v1_g26428 |
| Uniprot term | Description |
|---|---|
| P54886 | Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 |
| Q5R4M8 | Delta-1-pyrroline-5-carboxylate synthase OS=Pongo abelii OX=9601 GN=ALDH18A1 PE=2 SV=1 |
| Q9Z110 | Delta-1-pyrroline-5-carboxylate synthase OS=Mus musculus OX=10090 GN=Aldh18a1 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00696 | AA_kinase | Amino acid kinase family | Family | Interproscan |
| PF00171 | Aldedh | Aldehyde dehydrogenase family | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001048 | Domain | Aspartate/glutamate/uridylate kinase | Interproscan |
| IPR000965 | Domain | GPR domain | Interproscan |
| IPR020593 | Conserved_site | Gamma-glutamyl phosphate reductase GPR, conserved site | Interproscan |
| IPR036393 | Homologous_superfamily | Acetylglutamate kinase-like superfamily | Interproscan |
| IPR005766 | Family | Delta l-pyrroline-5-carboxylate synthetase | Interproscan |
| IPR001057 | Family | Glutamate/acetylglutamate kinase | Interproscan |
| IPR016161 | Homologous_superfamily | Aldehyde/histidinol dehydrogenase | Interproscan |
| IPR016162 | Homologous_superfamily | Aldehyde dehydrogenase, N-terminal | Interproscan |
| IPR005715 | Family | Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase | Interproscan |
| IPR041744 | Domain | Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain | Interproscan |
| IPR015590 | Domain | Aldehyde dehydrogenase domain | Interproscan |
| IPR019797 | Conserved_site | Glutamate 5-kinase, conserved site | Interproscan |
| IPR016163 | Homologous_superfamily | Aldehyde dehydrogenase, C-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11063 | GLUTAMATE SEMIALDEHYDE DEHYDROGENASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004350 | Molecular Function | glutamate-5-semialdehyde dehydrogenase activity | Interproscan |
| GO:0006561 | Biological Process | proline biosynthetic process | Interproscan |
| GO:0003824 | Molecular Function | catalytic activity | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0016301 | Molecular Function | kinase activity | Interproscan |
| GO:0016491 | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0004349 | Molecular Function | glutamate 5-kinase activity | Interproscan |
| GO:0016620 | Molecular Function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K12657 | ALDH18A1, P5CS; delta-1-pyrroline-5-carboxylate synthetase | EC:2.7.2.11 EC:1.2.1.41 | Arginine and proline metabolism | ko00330 | deepkoala |