Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr_11:14449279...14491573
NR annotation: XP_031566658.1, dedicator of cytokinesis protein 7-like [Actinia tenebrosa]
| CDS | |
| alvinactis_v1_g21793 | |
| Transcript |
| alvinactis_v1_g21793 |
| Protein |
| alvinactis_v1_g21793 |
| Uniprot term | Description |
|---|---|
| Q96N67 | Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4 |
| Q8R1A4 | Dedicator of cytokinesis protein 7 OS=Mus musculus OX=10090 GN=Dock7 PE=1 SV=3 |
| Q96HP0 | Dedicator of cytokinesis protein 6 OS=Homo sapiens OX=9606 GN=DOCK6 PE=1 SV=3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF11878 | DOCK_C-D_N | Dedicator of cytokinesis C/D, N terminal | Domain | Interproscan |
| PF20422 | DHR-2_Lobe_B | DHR-2, Lobe B | Domain | Interproscan |
| PF20421 | DHR-2_Lobe_C | DHR-2, Lobe C | Repeat | Interproscan |
| PF06920 | DHR-2_Lobe_A | DHR-2, Lobe A | Repeat | Interproscan |
| PF14429 | DOCK-C2 | C2 domain in Dock180 and Zizimin proteins | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR026791 | Family | Dedicator of cytokinesis | Interproscan |
| IPR027357 | Domain | DOCKER domain | Interproscan |
| IPR043161 | Homologous_superfamily | Dedicator of cytokinesis, C-terminal, lobe A | Interproscan |
| IPR043162 | Homologous_superfamily | Dedicator of cytokinesis, C-terminal, lobe C | Interproscan |
| IPR021816 | Domain | Dedicator of cytokinesis C/D, N-terminal | Interproscan |
| IPR046770 | Domain | DOCKER, Lobe B | Interproscan |
| IPR016024 | Homologous_superfamily | Armadillo-type fold | Interproscan |
| IPR037808 | Domain | Dedicator of cytokinesis C, C2 domain | Interproscan |
| IPR046773 | Domain | DOCKER, Lobe C | Interproscan |
| IPR035892 | Homologous_superfamily | C2 domain superfamily | Interproscan |
| IPR046769 | Domain | DOCKER, Lobe A | Interproscan |
| IPR027007 | Domain | C2 DOCK-type domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23317 | DEDICATOR OF CYTOKINESIS DOCK | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0007264 | Biological Process | small GTPase-mediated signal transduction | Interproscan |
| GO:0043547 | Biological Process | positive regulation of GTPase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K21852 | DOCK6_7_8; dedicator of cytokinesis protein 6/7/8 | - | Membrane trafficking | ko04131 | deepkoala |