Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr_11:6218848...6240062
NR annotation: XP_031564897.1, very low-density lipoprotein receptor-like isoform X5 [Actinia tenebrosa]
| CDS | |
| alvinactis_v1_g21290 | |
| Transcript |
| alvinactis_v1_g21290 |
| Protein |
| alvinactis_v1_g21290 |
| Uniprot term | Description |
|---|---|
| A2ARV4 | Low-density lipoprotein receptor-related protein 2 OS=Mus musculus OX=10090 GN=Lrp2 PE=1 SV=1 |
| P98158 | Low-density lipoprotein receptor-related protein 2 OS=Rattus norvegicus OX=10116 GN=Lrp2 PE=1 SV=1 |
| P98164 | Low-density lipoprotein receptor-related protein 2 OS=Homo sapiens OX=9606 GN=LRP2 PE=1 SV=3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00057 | Ldl_recept_a | Low-density lipoprotein receptor domain class A | Repeat | Interproscan |
| PF07645 | EGF_CA | Calcium-binding EGF domain | Domain | Interproscan |
| PF14670 | FXa_inhibition | Coagulation Factor Xa inhibitory site | Domain | Interproscan |
| PF00058 | Ldl_recept_b | Low-density lipoprotein receptor repeat class B | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002172 | Repeat | Low-density lipoprotein (LDL) receptor class A repeat | Interproscan |
| IPR000152 | PTM | EGF-type aspartate/asparagine hydroxylation site | Interproscan |
| IPR023415 | Conserved_site | Low-density lipoprotein (LDL) receptor class A, conserved site | Interproscan |
| IPR036055 | Homologous_superfamily | LDL receptor-like superfamily | Interproscan |
| IPR000742 | Domain | EGF-like domain | Interproscan |
| IPR000033 | Repeat | LDLR class B repeat | Interproscan |
| IPR011042 | Homologous_superfamily | Six-bladed beta-propeller, TolB-like | Interproscan |
| IPR049883 | Domain | NOTCH1 EGF-like calcium-binding domain | Interproscan |
| IPR009030 | Homologous_superfamily | Growth factor receptor cysteine-rich domain superfamily | Interproscan |
| IPR051221 | Family | Low-density lipoprotein receptor-related | Interproscan |
| IPR001881 | Domain | EGF-like calcium-binding domain | Interproscan |
| IPR018097 | Conserved_site | EGF-like calcium-binding, conserved site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22722 | LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0006898 | Biological Process | receptor-mediated endocytosis | Interproscan |
| GO:0016324 | Cellular Component | apical plasma membrane | Interproscan |
| GO:0042562 | Molecular Function | hormone binding | Interproscan |
| GO:0043235 | Cellular Component | receptor complex | Interproscan |
| GO:0005509 | Molecular Function | calcium ion binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K20053 | VLDLR; very low-density lipoprotein receptor | - | Membrane trafficking | ko04131 | deepkoala |