Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr_10:22655837...22676087
NR annotation: XP_028514684.1, serine/threonine-protein kinase A-Raf [Exaiptasia diaphana]
| CDS | |
| alvinactis_v1_g20748 | |
| Transcript |
| alvinactis_v1_g20748 |
| Protein |
| alvinactis_v1_g20748 |
| Uniprot term | Description |
|---|---|
| P15056 | Serine/threonine-protein kinase B-raf OS=Homo sapiens OX=9606 GN=BRAF PE=1 SV=4 |
| Q04982 | Serine/threonine-protein kinase B-raf OS=Gallus gallus OX=9031 GN=BRAF PE=1 SV=2 |
| P28028 | Serine/threonine-protein kinase B-raf OS=Mus musculus OX=10090 GN=Braf PE=1 SV=4 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00130 | C1_1 | Phorbol esters/diacylglycerol binding domain (C1 domain) | Domain | Interproscan |
| PF02196 | RBD | Raf-like Ras-binding domain | Domain | Interproscan |
| PF07714 | PK_Tyr_Ser-Thr | Protein tyrosine and serine/threonine kinase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR046349 | Homologous_superfamily | C1-like domain superfamily | Interproscan |
| IPR050167 | Family | Serine/threonine-protein kinase | Interproscan |
| IPR002219 | Domain | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Interproscan |
| IPR003116 | Domain | Raf-like Ras-binding | Interproscan |
| IPR017441 | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR001245 | Domain | Serine-threonine/tyrosine-protein kinase, catalytic domain | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR029071 | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23257 | SERINE-THREONINE PROTEIN KINASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0007165 | Biological Process | signal transduction | Interproscan |
| GO:0007265 | Biological Process | Ras protein signal transduction | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K04365 | BRAF; B-Raf proto-oncogene serine/threonine-protein kinase | EC:2.7.11.1 | Protein kinases | ko01001 | deepkoala |