Genomic Location: chr_8:19195216...19206851
NR annotation: XP_020892026.1, cholesterol 24-hydroxylase [Exaiptasia diaphana]
| CDS | |
| alvinactis_v1_g17158 | |
| Transcript |
| alvinactis_v1_g17158 |
| Protein |
| alvinactis_v1_g17158 |
| Uniprot term | Description |
|---|---|
| Q9WVK8 | Cholesterol 24-hydroxylase OS=Mus musculus OX=10090 GN=Cyp46a1 PE=1 SV=1 |
| Q9Y6A2 | Cholesterol 24-hydroxylase OS=Homo sapiens OX=9606 GN=CYP46A1 PE=1 SV=1 |
| Q6QA33 | Very-long-chain 3-oxoacyl-CoA reductase-B OS=Danio rerio OX=7955 GN=hsd17b12b PE=2 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00106 | adh_short | short chain dehydrogenase | Domain | Interproscan |
| PF00067 | p450 | Cytochrome P450 | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002347 | Family | Short-chain dehydrogenase/reductase SDR | Interproscan |
| IPR002401 | Family | Cytochrome P450, E-class, group I | Interproscan |
| IPR020904 | Conserved_site | Short-chain dehydrogenase/reductase, conserved site | Interproscan |
| IPR036396 | Homologous_superfamily | Cytochrome P450 superfamily | Interproscan |
| IPR017972 | Conserved_site | Cytochrome P450, conserved site | Interproscan |
| IPR001128 | Family | Cytochrome P450 | Interproscan |
| IPR039983 | Family | Cholesterol 24-hydroxylase | Interproscan |
| IPR036291 | Homologous_superfamily | NAD(P)-binding domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR24293 | CYTOCHROME P450 FAMILY 46 SUBFAMILY A | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004497 | Molecular Function | monooxygenase activity | Interproscan |
| GO:0005506 | Molecular Function | iron ion binding | Interproscan |
| GO:0016705 | Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Interproscan |
| GO:0020037 | Molecular Function | heme binding | Interproscan |
| GO:0016491 | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0006707 | Biological Process | cholesterol catabolic process | Interproscan |
| GO:0033781 | Molecular Function | cholesterol 24-hydroxylase activity | Interproscan |