Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: chr_1:22697352...22703571
NR annotation: XP_020916732.1, D-3-phosphoglycerate dehydrogenase [Exaiptasia diaphana]
| CDS | |
| alvinactis_v1_g1340 | |
| Transcript |
| alvinactis_v1_g1340 |
| Protein |
| alvinactis_v1_g1340 |
| Uniprot term | Description |
|---|---|
| Q5EAD2 | D-3-phosphoglycerate dehydrogenase OS=Bos taurus OX=9913 GN=PHGDH PE=2 SV=3 |
| Q61753 | D-3-phosphoglycerate dehydrogenase OS=Mus musculus OX=10090 GN=Phgdh PE=1 SV=3 |
| Q60HD7 | D-3-phosphoglycerate dehydrogenase OS=Macaca fascicularis OX=9541 GN=PHGDH PE=2 SV=4 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF19304 | PGDH_inter | D-3-phosphoglycerate dehydrogenase intervening domain | Domain | Interproscan |
| PF02826 | 2-Hacid_dh_C | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain | Domain | Interproscan |
| PF00389 | 2-Hacid_dh | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR029009 | Homologous_superfamily | Allosteric substrate binding domain superfamily | Interproscan |
| IPR045626 | Domain | D-3-phosphoglycerate dehydrogenase, ASB domain | Interproscan |
| IPR006236 | Family | D-3-phosphoglycerate dehydrogenase | Interproscan |
| IPR029753 | Conserved_site | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site | Interproscan |
| IPR006140 | Domain | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain | Interproscan |
| IPR006139 | Domain | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | Interproscan |
| IPR029752 | Conserved_site | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 | Interproscan |
| IPR036291 | Homologous_superfamily | NAD(P)-binding domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR42938 | FORMATE DEHYDROGENASE 1 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004617 | Molecular Function | phosphoglycerate dehydrogenase activity | Interproscan |
| GO:0006564 | Biological Process | L-serine biosynthetic process | Interproscan |
| GO:0051287 | Molecular Function | NAD binding | Interproscan |
| GO:0016616 | Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00058 | serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase | EC:1.1.1.95 EC:1.1.1.399 | Exosome | ko04147 | deepkoala |