Genomic Location: chr_5:13778644...13847798
NR annotation: XP_031552768.1, glutathione reductase, mitochondrial-like [Actinia tenebrosa]
| CDS | |
| alvinactis_v1_g10903 | |
| Transcript |
| alvinactis_v1_g10903 |
| Protein |
| alvinactis_v1_g10903 |
| Uniprot term | Description |
|---|---|
| P00390 | Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2 |
| P47791 | Glutathione reductase, mitochondrial OS=Mus musculus OX=10090 GN=Gsr PE=1 SV=3 |
| A2TIL1 | Glutathione reductase, mitochondrial OS=Callithrix jacchus OX=9483 GN=GSR PE=2 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02852 | Pyr_redox_dim | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain | Domain | Interproscan |
| PF07992 | Pyr_redox_2 | Pyridine nucleotide-disulphide oxidoreductase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036188 | Homologous_superfamily | FAD/NAD(P)-binding domain superfamily | Interproscan |
| IPR016156 | Homologous_superfamily | FAD/NAD-linked reductase, dimerisation domain superfamily | Interproscan |
| IPR046952 | Family | Glutathione reductase/thioredoxin reductase-like | Interproscan |
| IPR001100 | Family | Pyridine nucleotide-disulphide oxidoreductase, class I | Interproscan |
| IPR004099 | Domain | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain | Interproscan |
| IPR006322 | Family | Glutathione reductase, eukaryote/bacterial | Interproscan |
| IPR012999 | Active_site | Pyridine nucleotide-disulphide oxidoreductase, class I, active site | Interproscan |
| IPR023753 | Domain | FAD/NAD(P)-binding domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR42737 | GLUTATHIONE REDUCTASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0016491 | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0050660 | Molecular Function | flavin adenine dinucleotide binding | Interproscan |
| GO:0004362 | Molecular Function | glutathione-disulfide reductase (NADPH) activity | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0005829 | Cellular Component | cytosol | Interproscan |
| GO:0006749 | Biological Process | glutathione metabolic process | Interproscan |
| GO:0034599 | Biological Process | cellular response to oxidative stress | Interproscan |
| GO:0045454 | Biological Process | cell redox homeostasis | Interproscan |
| GO:0050661 | Molecular Function | NADP binding | Interproscan |
| GO:0016668 | Molecular Function | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00383 | GSR, gor; glutathione reductase (NADPH) | EC:1.8.1.7 | Diabetic cardiomyopathy | ko05415 | deepkoala |