Genomic Location: scaffold_238:204996...212108
NR annotation: KAJ7370421.1, Breast cancer 1, early onset [Desmophyllum pertusum]
| CDS | ||||
| OS493_032311-T1 | ||||
| Transcript |
| OS493_032311-T1 |
| Protein |
| OS493_032311-T1 |
| Uniprot term | Description |
|---|---|
| Q6J6I9 | Breast cancer type 1 susceptibility protein homolog OS=Macaca mulatta OX=9544 GN=BRCA1 PE=3 SV=1 |
| Q6J6J0 | Breast cancer type 1 susceptibility protein homolog OS=Pongo pygmaeus OX=9600 GN=BRCA1 PE=3 SV=1 |
| Q6J6I8 | Breast cancer type 1 susceptibility protein homolog OS=Gorilla gorilla gorilla OX=9595 GN=BRCA1 PE=3 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | E3|E3 activity RING|RING |
| Ubiquitin Family | E3|E3 activity RING|U-box |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00097 | zf-C3HC4 | Zinc finger, C3HC4 type (RING finger) | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR018957 | Domain | Zinc finger, C3HC4 RING-type | Interproscan |
| IPR001841 | Domain | Zinc finger, RING-type | Interproscan |
| IPR031099 | Family | BRCA1-associated | Interproscan |
| IPR017907 | Conserved_site | Zinc finger, RING-type, conserved site | Interproscan |
| IPR013083 | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13763 | BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| GO:0000724 | Biological Process | double-strand break repair via homologous recombination | Interproscan |
| GO:0004842 | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0006281 | Biological Process | DNA repair | Interproscan |
| GO:0006974 | Biological Process | DNA damage response | Interproscan |
| GO:0031436 | Cellular Component | BRCA1-BARD1 complex | Interproscan |
| GO:0035066 | Biological Process | obsolete positive regulation of histone acetylation | Interproscan |
| GO:0035067 | Biological Process | obsolete negative regulation of histone acetylation | Interproscan |
| GO:0045717 | Biological Process | negative regulation of fatty acid biosynthetic process | Interproscan |
| GO:0045944 | Biological Process | positive regulation of transcription by RNA polymerase II | Interproscan |
| GO:0070531 | Cellular Component | BRCA1-A complex | Interproscan |
| Expression trend for OS493_032311-T1 global co-expression network |