Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
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Genomic Location: scaffold_97:325347...353262
NR annotation: KAJ7390711.1, tRNA methyltransferase 1 [Desmophyllum pertusum]
| CDS | |
| OS493_022790-T1 | |
| Transcript |
| OS493_022790-T1 |
| Protein |
| OS493_022790-T1 |
| Uniprot term | Description |
|---|---|
| Q9NXH9 | tRNA (guanine(26)-N(2))-dimethyltransferase OS=Homo sapiens OX=9606 GN=TRMT1 PE=1 SV=1 |
| Q3TX08 | tRNA (guanine(26)-N(2))-dimethyltransferase OS=Mus musculus OX=10090 GN=Trmt1 PE=1 SV=3 |
| Q9VK89 | tRNA (guanine(26)-N(2))-dimethyltransferase OS=Drosophila melanogaster OX=7227 GN=Trm1 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02005 | TRM | N2,N2-dimethylguanosine tRNA methyltransferase | Family | Interproscan |
| PF00642 | zf-CCCH | Zinc finger C-x8-C-x5-C-x3-H type (and similar) | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002905 | Family | tRNA methyltransferase, Trm1 | Interproscan |
| IPR000571 | Domain | Zinc finger, CCCH-type | Interproscan |
| IPR029063 | Homologous_superfamily | S-adenosyl-L-methionine-dependent methyltransferase superfamily | Interproscan |
| IPR042296 | Homologous_superfamily | tRNA methyltransferase, Trm1, C-terminal | Interproscan |
| IPR036855 | Homologous_superfamily | Zinc finger, CCCH-type superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10631 | N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0003723 | Molecular Function | RNA binding | Interproscan |
| GO:0008033 | Biological Process | tRNA processing | Interproscan |
| GO:0160102 | Molecular Function | tRNA (guanine(10)-N2)-methyltransferase activity | Interproscan |
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| GO:0002940 | Biological Process | tRNA N2-guanine methylation | Interproscan |
| GO:0004809 | Molecular Function | obsolete tRNA (guanine-N2-)-methyltransferase activity | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00555 | TRMT1, trm1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase | EC:2.1.1.215 EC:2.1.1.216 | Transfer RNA biogenesis | ko03016 | deepkoala |
| Expression trend for OS493_022790-T1 global co-expression network |