Genomic Location: ctg197:429683...493093
NR annotation: XP_028514045.1, probable E3 ubiquitin-protein ligase HERC1 isoform X1 [Exaiptasia diaphana]
| CDS | |||||
| HK74SY85_g18446 | |||||
| Transcript |
| HK74SY85_g18446 |
| Protein |
| HK74SY85_g18446 |
| Uniprot term | Description |
|---|---|
| Q15751 | Probable E3 ubiquitin-protein ligase HERC1 OS=Homo sapiens OX=9606 GN=HERC1 PE=1 SV=2 |
| Q4U2R1 | E3 ubiquitin-protein ligase HERC2 OS=Mus musculus OX=10090 GN=Herc2 PE=1 SV=3 |
| O95714 | E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens OX=9606 GN=HERC2 PE=1 SV=2 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Other|Beta-prp |
| Ubiquitin Family | E3|E3 adaptor Cullin RING|CDC20 |
| Ubiquitin Family | E3|E3 activity|HECT |
| Ubiquitin Family | E3|E3 adaptor Cullin RING|DWD |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00632 | HECT | HECT-domain (ubiquitin-transferase) | Domain | Interproscan |
| PF00622 | SPRY | SPRY domain | Family | Interproscan |
| PF00400 | WD40 | WD domain, G-beta repeat | Repeat | Interproscan |
| PF00415 | RCC1 | Regulator of chromosome condensation (RCC1) repeat | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000408 | Repeat | Regulator of chromosome condensation, RCC1 | Interproscan |
| IPR001870 | Domain | B30.2/SPRY domain | Interproscan |
| IPR000569 | Domain | HECT domain | Interproscan |
| IPR015943 | Homologous_superfamily | WD40/YVTN repeat-like-containing domain superfamily | Interproscan |
| IPR003877 | Domain | SPRY domain | Interproscan |
| IPR035768 | Domain | HERC1, SPRY domain | Interproscan |
| IPR051625 | Family | Diverse Signaling and Regulatory Domain-Containing Protein | Interproscan |
| IPR009091 | Homologous_superfamily | Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II | Interproscan |
| IPR001680 | Repeat | WD40 repeat | Interproscan |
| IPR013320 | Homologous_superfamily | Concanavalin A-like lectin/glucanase domain superfamily | Interproscan |
| IPR043136 | Homologous_superfamily | B30.2/SPRY domain superfamily | Interproscan |
| IPR019775 | Conserved_site | WD40 repeat, conserved site | Interproscan |
| IPR036322 | Homologous_superfamily | WD40-repeat-containing domain superfamily | Interproscan |
| IPR035983 | Homologous_superfamily | HECT, E3 ligase catalytic domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22872 | BTK-BINDING PROTEIN-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004842 | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K10594 | HERC1; E3 ubiquitin-protein ligase HERC1 | EC:2.3.2.26 | Ubiquitin system | ko04121 | deepkoala |