Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
© 2024 All Rights Reserved.
Genomic Location: ctg90:617850...630450
NR annotation: KXJ12564.1, Apoptosis-inducing factor 1, mitochondrial [Exaiptasia diaphana]
| CDS | |
| HK74SY85_g12171 | |
| Transcript |
| HK74SY85_g12171 |
| Protein |
| HK74SY85_g12171 |
| Uniprot term | Description |
|---|---|
| O95831 | Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1 |
| Q9JM53 | Apoptosis-inducing factor 1, mitochondrial OS=Rattus norvegicus OX=10116 GN=Aifm1 PE=1 SV=1 |
| Q9Z0X1 | Apoptosis-inducing factor 1, mitochondrial OS=Mus musculus OX=10090 GN=Aifm1 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF14721 | AIF_C | Apoptosis-inducing factor, mitochondrion-associated, C-term | Domain | Interproscan |
| PF07992 | Pyr_redox_2 | Pyridine nucleotide-disulphide oxidoreductase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036188 | Homologous_superfamily | FAD/NAD(P)-binding domain superfamily | Interproscan |
| IPR029324 | Domain | Mitochondrial apoptosis-inducing factor, C-terminal domain | Interproscan |
| IPR023753 | Domain | FAD/NAD(P)-binding domain | Interproscan |
| IPR050446 | Family | FAD-dependent Oxidoreductases and Apoptosis Regulators | Interproscan |
| IPR016156 | Homologous_superfamily | FAD/NAD-linked reductase, dimerisation domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43557 | APOPTOSIS-INDUCING FACTOR 1 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0046983 | Molecular Function | protein dimerization activity | Interproscan |
| GO:0016491 | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0005739 | Cellular Component | mitochondrion | Interproscan |
| GO:0006915 | Biological Process | apoptotic process | Interproscan |
| GO:0012501 | Biological Process | programmed cell death | Interproscan |
| GO:0016174 | Molecular Function | NAD(P)H oxidase H2O2-forming activity | Interproscan |
| GO:0016651 | Molecular Function | oxidoreductase activity, acting on NAD(P)H | Interproscan |
| GO:0033108 | Biological Process | mitochondrial respiratory chain complex assembly | Interproscan |
| GO:0071949 | Molecular Function | FAD binding | Interproscan |
| GO:0050660 | Molecular Function | flavin adenine dinucleotide binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K04727 | AIFM1, PDCD8; apoptosis-inducing factor 1 | EC:1.-.-.- | Necroptosis | ko04217 | deepkoala |