Maintained by Dr. Jiajie She in Longjun Wu's Lab & Pei-Yuan Qian's Lab and supported by Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) & The Hong Kong University of Science and Technology
© 2024 All Rights Reserved.
Genomic Location: ctg85:410215...425987
NR annotation: KXJ16807.1, S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [Exaiptasia diaphana]
| CDS | |
| HK74SY85_g11827 | |
| Transcript |
| HK74SY85_g11827 |
| Protein |
| HK74SY85_g11827 |
| Uniprot term | Description |
|---|---|
| Q2KHP8 | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 OS=Xenopus laevis OX=8355 GN=tyw1 PE=2 SV=1 |
| Q5REF9 | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 OS=Pongo abelii OX=9601 GN=TYW1 PE=2 SV=1 |
| Q9NV66 | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 OS=Homo sapiens OX=9606 GN=TYW1 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08608 | Wyosine_form | Wyosine base formation | Family | Interproscan |
| PF00258 | Flavodoxin_1 | Flavodoxin | Domain | Interproscan |
| PF04055 | Radical_SAM | Radical SAM superfamily | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001094 | Domain | Flavodoxin-like | Interproscan |
| IPR008254 | Domain | Flavodoxin/nitric oxide synthase | Interproscan |
| IPR013917 | Domain | tRNA wybutosine-synthesis | Interproscan |
| IPR034556 | Family | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase | Interproscan |
| IPR029039 | Homologous_superfamily | Flavoprotein-like superfamily | Interproscan |
| IPR007197 | Domain | Radical SAM | Interproscan |
| IPR013785 | Homologous_superfamily | Aldolase-type TIM barrel | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR13930 | S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0010181 | Molecular Function | FMN binding | Interproscan |
| GO:0008033 | Biological Process | tRNA processing | Interproscan |
| GO:0051539 | Molecular Function | 4 iron, 4 sulfur cluster binding | Interproscan |
| GO:0003824 | Molecular Function | catalytic activity | Interproscan |
| GO:0051536 | Molecular Function | iron-sulfur cluster binding | Interproscan |
| GO:0031591 | Biological Process | wybutosine biosynthetic process | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K15449 | TYW1; tRNA wybutosine-synthesizing protein 1 | EC:4.1.3.44 | Transfer RNA biogenesis | ko03016 | deepkoala |